How would you like your COVID-19? From a host with mild course disease, or from a severe one?
Host factor in COVID-19
Novel coronavirus
SARS-CoV-2
Source of coronavirus
Subtypes of novel coronavirus
Journal
The American journal of emergency medicine
ISSN: 1532-8171
Titre abrégé: Am J Emerg Med
Pays: United States
ID NLM: 8309942
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
20
05
2020
accepted:
29
05
2020
pubmed:
17
6
2020
medline:
18
12
2020
entrez:
16
6
2020
Statut:
ppublish
Résumé
The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variable clinical courses among the similar individuals in terms of age and chronic diseases are also seen. Other possible factors affecting the course of the disease that are mostly speculative or under investigation are genetic factors and the origin of transmission or possible subtype of novel coronavirus. Whether the source of transmission is important in the clinical course of the disease is unknown. A case series composed of seven individuals in a similar age group, with different lines of descent and different genetic structures, but who were infected from the same source is presented here. The similar and different clinical, laboratory and radiological findings of the cases residing in the same nursing home, who presented to the hospital altogether, were evaluated. The aim of the study was to analyze whether the source of transmission is influential in the clinical course of the disease.
Identifiants
pubmed: 32536478
pii: S0735-6757(20)30453-8
doi: 10.1016/j.ajem.2020.05.091
pmc: PMC7834627
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
2487.e7-2487.e12Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors had no conflicts of interest to declare in relation to this article.
Références
Lancet. 2020 Feb 15;395(10223):514-523
pubmed: 31986261
Mil Med Res. 2020 Mar 13;7(1):11
pubmed: 32169119
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Int J Infect Dis. 2020 Jul;96:452-453
pubmed: 32194239
Proc Natl Acad Sci U S A. 2020 Apr 28;117(17):9241-9243
pubmed: 32269081
Trop Med Int Health. 2020 Mar;25(3):278-280
pubmed: 32052514
Clin Infect Dis. 2020 Aug 04;:
pubmed: 32750119
Acta Biomed. 2020 Mar 19;91(1):157-160
pubmed: 32191675
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Clin Infect Dis. 2020 Jul 28;71(15):861-862
pubmed: 32201889