Adherence to antiretroviral therapy among HIV infected pregnant women in public health sectors: a pilot of Chilenje level one Hospital Lusaka, Zambia.
Adolescent
Adult
Age Factors
Anti-HIV Agents
/ administration & dosage
Cross-Sectional Studies
Female
HIV Infections
/ drug therapy
Humans
Infectious Disease Transmission, Vertical
/ prevention & control
Marital Status
Medication Adherence
/ statistics & numerical data
Pilot Projects
Pregnancy
Pregnancy Complications, Infectious
/ drug therapy
Prenatal Care
Public Sector
Young Adult
Zambia
HIV
Zambia
adherence
antiretroviral therapy (Option B+)
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
08
2019
accepted:
24
08
2019
entrez:
16
6
2020
pubmed:
17
6
2020
medline:
29
12
2020
Statut:
epublish
Résumé
regular use of Antiretroviral Therapy (ART) in pregnancy and breastfeeding reduces the odds of Mother-to-Child HIV Transmission (MTCT). However, adherence to ART is critical for MTCT to be successful. The present study investigated factors that influence adherence to ART among HIV infected pregnant women in Zambia. a cross-sectional study design was conducted involving 71 HIV infected pregnant women who were advised to join the Prevention of Mother-to-Child HIV Transmission (PMTCT) program during their routine Antenatal clinic (ANC) visit and were on ART for more than six months. We used the Medication Possession Ratio (MPR) to quantify adherence levels. We used logistic regression to establish factors that influence adherence to ART. a total of 71 HIV infected pregnant women with a median age of 27years (IQR, 25-30) were enrolled in the study. There was evidence of a difference in adherence levels between pregnant women above 30 years and ones between 15 years and 30 years (P<0.001). Median adherence levels in this group were found to be at 96%(IQR 89-97). The main predictor of adherence in this population was marital status (being on separation) and age. The women who were on separation were 0.14 times less likely to adhere to option B+ compared to married women. adherence to option B+ among pregnant women is low. Adherence was significantly influenced by marital status (being on separation) and age. Efforts to improve adherence should be directed towards women on separation and young adults (< 30 years of age).
Identifiants
pubmed: 32537054
doi: 10.11604/pamj.2020.35.49.20078
pii: PAMJ-35-49
pmc: PMC7250199
doi:
Substances chimiques
Anti-HIV Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
49Informations de copyright
© Moses Mukosha et al.
Déclaration de conflit d'intérêts
The author declares no competing interests.
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