Construction and forensic application of 20 highly polymorphic microhaplotypes.
genetic markers
individual identification
microhaplotype
Journal
Royal Society open science
ISSN: 2054-5703
Titre abrégé: R Soc Open Sci
Pays: England
ID NLM: 101647528
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
05
11
2019
accepted:
07
04
2020
entrez:
16
6
2020
pubmed:
17
6
2020
medline:
17
6
2020
Statut:
epublish
Résumé
Microhaplotype markers have become an important research focus in forensic genetics. However, many reported microhaplotype markers have limited polymorphisms. In this study, we developed a set of highly polymorphic microhaplotype markers based on tri-allelic single-nucleotide polymorphisms. Eleven newly discovered microhaplotypes along with nine previously identified in our laboratory were studied. The microhaplotype genotypes of unrelated individuals and familial samples were generated on the MiSeq PE300 platform. These 20 loci have an average greater than 3.5 effective number of alleles. Over the whole set, the cumulative power of discrimination was 1-3.3 × 10
Identifiants
pubmed: 32537197
doi: 10.1098/rsos.191937
pii: rsos191937
pmc: PMC7277291
doi:
Banques de données
figshare
['10.6084/m9.figshare.c.4964081']
Types de publication
Journal Article
Langues
eng
Pagination
191937Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
We have no competing interests.
Références
Mol Biol Evol. 2010 Apr;27(4):747-52
pubmed: 20022889
Genome Res. 2017 May;27(5):801-812
pubmed: 27940952
BMC Genomics. 2014 Mar 10;15:184
pubmed: 24612714
Mol Biol Evol. 2003 Dec;20(12):2123-31
pubmed: 12949124
Hum Genomics. 2016 Jun 17;10(1):16
pubmed: 27316555
Forensic Sci Int. 1994 Feb;64(2-3):125-40
pubmed: 8175083
Int J Legal Med. 2019 May;133(3):719-729
pubmed: 30758713
Cell Res. 2005 Feb;15(2):97-8
pubmed: 15740637
Mol Ecol Resour. 2010 May;10(3):564-7
pubmed: 21565059
Forensic Sci Int. 2005 Nov 25;154(2-3):181-94
pubmed: 16182964
Forensic Sci Int Genet. 2019 May;40:140-149
pubmed: 30836262
Bioinformatics. 2007 Jul 15;23(14):1801-6
pubmed: 17485429
Investig Genet. 2015 Jan 28;6:1
pubmed: 25750707
Am J Hum Genet. 2005 Mar;76(3):449-62
pubmed: 15700229
Forensic Sci Int Genet. 2017 Jul;29:29-37
pubmed: 28359046
Forensic Sci Int Genet. 2019 Mar;39:1-7
pubmed: 30472641
Am J Hum Genet. 2001 Apr;68(4):978-89
pubmed: 11254454
Electrophoresis. 2019 Apr;40(7):1091-1095
pubmed: 30557455
Forensic Sci Int Genet. 2014 Sep;12:215-24
pubmed: 25038325
Forensic Sci Int Genet. 2018 Jul;35:169-175
pubmed: 29852469
Eur J Hum Genet. 2012 Nov;20(11):1148-54
pubmed: 22535184
Forensic Sci Int Genet. 2014 Sep;12:107-19
pubmed: 24908576
Mol Biol Evol. 1987 Jul;4(4):406-25
pubmed: 3447015
Forensic Sci Med Pathol. 2007 Sep;3(3):200-5
pubmed: 25869164
Forensic Sci Int Genet. 2018 Jul;35:149-155
pubmed: 29778046
Nat Rev Genet. 2006 Oct;7(10):771-80
pubmed: 16983373
Int J Legal Med. 2019 Jul;133(4):983-988
pubmed: 29936540
Int J Legal Med. 2018 May;132(3):703-711
pubmed: 29248957
Electrophoresis. 2018 Nov;39(21):2815-2823
pubmed: 29931757
Gene. 1999 Jul 8;234(2):177-86
pubmed: 10395891
Int J Legal Med. 2001;114(4-5):204-10
pubmed: 11355396
Forensic Sci Int Genet. 2015 Sep;18:78-89
pubmed: 25704953
Nature. 2015 Oct 1;526(7571):68-74
pubmed: 26432245
Forensic Sci Int Genet. 2012 Dec;6(6):810-8
pubmed: 22503403
Science. 2002 Dec 20;298(5602):2381-5
pubmed: 12493913
Curr Protoc Bioinformatics. 2013;43:11.10.1-11.10.33
pubmed: 25431634
Nat Genet. 2002 Sep;32(1):135-42
pubmed: 12161752
Forensic Sci Int Genet. 2019 Jul;41:120-127
pubmed: 31071520
Curr Biol. 2016 Apr 4;26(7):935-42
pubmed: 26996508
Mol Biol Evol. 2016 Jul;33(7):1870-4
pubmed: 27004904