Efficacy of Osteopathic Manipulative Treatment on postural control in Parkinsonian patients with Pisa syndrome: A pilot randomized placebo-controlled trial.


Journal

NeuroRehabilitation
ISSN: 1878-6448
Titre abrégé: NeuroRehabilitation
Pays: Netherlands
ID NLM: 9113791

Informations de publication

Date de publication:
2020
Historique:
pubmed: 17 6 2020
medline: 21 11 2020
entrez: 16 6 2020
Statut: ppublish

Résumé

Pisa syndrome (PS) is a clinical condition frequently associated with Parkinson's disease (PD). It is characterized by a trunk lateral flexion higher than 10 degrees and reversible when lying. One pathophysiological hypothesis is the altered verticality perception, due to a somatosensory impairment. Osteopathic Manipulative Treatment (OMT) manages fascial-system alterations, linked to somatic dysfunctions. Fascial system showed to be implicated in proprioceptive sensibility. The aim of the study was to assess OMT efficacy on postural control in PD-PS patients by stabilometry. In this single-blinded trial we studied 24 PD-PS patients, 12 of whom were randomly assigned to receive a multidisciplinary physical therapy protocol (MIRT) and sham OMT, while the other 12 received four OMT plus MIRT, for one month. The primary endpoint was the eye closed sway area assessment after the intervention. Evaluation of trunk lateral flexion (TLF) with DIERS formetrics was also performed. At one month, the sway area of the OMT group significantly decreased compared to placebo (mean delta OMT - 326.00±491.24 mm2, p = 0.01). In the experimental group TLF showed a mean inclination reduction of 3.33 degrees after treatment (p = 0.044, mean d = 0.54). Moreover, a significant positive association between delta ECSA and delta TLF was observed (p = 0.04, r = 0.46). Among PD-PS patients, MIRT plus OMT showed preliminary evidence of postural control and TLF improvement, compared to the control group.

Sections du résumé

BACKGROUND BACKGROUND
Pisa syndrome (PS) is a clinical condition frequently associated with Parkinson's disease (PD). It is characterized by a trunk lateral flexion higher than 10 degrees and reversible when lying. One pathophysiological hypothesis is the altered verticality perception, due to a somatosensory impairment. Osteopathic Manipulative Treatment (OMT) manages fascial-system alterations, linked to somatic dysfunctions. Fascial system showed to be implicated in proprioceptive sensibility.
OBJECTIVE OBJECTIVE
The aim of the study was to assess OMT efficacy on postural control in PD-PS patients by stabilometry.
METHODS METHODS
In this single-blinded trial we studied 24 PD-PS patients, 12 of whom were randomly assigned to receive a multidisciplinary physical therapy protocol (MIRT) and sham OMT, while the other 12 received four OMT plus MIRT, for one month. The primary endpoint was the eye closed sway area assessment after the intervention. Evaluation of trunk lateral flexion (TLF) with DIERS formetrics was also performed.
RESULTS RESULTS
At one month, the sway area of the OMT group significantly decreased compared to placebo (mean delta OMT - 326.00±491.24 mm2, p = 0.01). In the experimental group TLF showed a mean inclination reduction of 3.33 degrees after treatment (p = 0.044, mean d = 0.54). Moreover, a significant positive association between delta ECSA and delta TLF was observed (p = 0.04, r = 0.46).
DISCUSSION CONCLUSIONS
Among PD-PS patients, MIRT plus OMT showed preliminary evidence of postural control and TLF improvement, compared to the control group.

Identifiants

pubmed: 32538880
pii: NRE203068
doi: 10.3233/NRE-203068
doi:

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

529-537

Auteurs

A Zarucchi (A)

Department of Brain Injury and Parkinson's Disease Rehabilitation, Ospedale "Moriggia-Pelascini", Gravedona ed Uniti (Como), Italy.
Department of Clinical Research, SOMA Istituto Osteopatia Milano, Italy.

L Vismara (L)

"Rita Levi Montalcini" Department of Neurosciences, University of Turin, Turin, Italy.
Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano Piancavallo-Verbania, Italy.
MANIMA, Not-for-Profit Healthcare and Assistance, Milan, Italy.

G Frazzitta (G)

Department of Brain Injury and Parkinson's Disease Rehabilitation, Ospedale "Moriggia-Pelascini", Gravedona ed Uniti (Como), Italy.

A Mauro (A)

"Rita Levi Montalcini" Department of Neurosciences, University of Turin, Turin, Italy.
Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano Piancavallo-Verbania, Italy.

L Priano (L)

"Rita Levi Montalcini" Department of Neurosciences, University of Turin, Turin, Italy.
Division of Neurology and Neurorehabilitation, IRCCS Istituto Auxologico Italiano Piancavallo-Verbania, Italy.

R Maestri (R)

Department of Biomedical Engineering, Istituti Clinici Scientifici Maugeri Spa Società Benefit, IRCCS, Montescano, Italy.

A Bergna (A)

Department of Clinical Research, SOMA Istituto Osteopatia Milano, Italy.

A G Tarantino (AG)

Department of Clinical Research, SOMA Istituto Osteopatia Milano, Italy.
MANIMA, Not-for-Profit Healthcare and Assistance, Milan, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH