Er:YAG laser promotes proliferation and wound healing capacity of human periodontal ligament fibroblasts through Galectin-7 induction.
Er:YAG laser
LGALS7
Periodontal ligament fibroblasts
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
ISSN: 0929-6646
Titre abrégé: J Formos Med Assoc
Pays: Singapore
ID NLM: 9214933
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
29
04
2020
revised:
21
05
2020
accepted:
03
06
2020
pubmed:
17
6
2020
medline:
24
2
2021
entrez:
17
6
2020
Statut:
ppublish
Résumé
Among various dental lasers, the erbium-doped yttrium-aluminum-garnet (Er:YAG) laser has great potential for periodontal treatment including soft and hard tissue ablation with minimal thermal side effects under suitable energy densities and it has multiple effects on tissues for wound-healing benefits. In the present study, we sought to reveal the molecular mechanism underlying the impact of Er:YAG laser on PDL fibroblasts. Cells were irradiated by a Er:YAG laser with various energy densities (3.6-6.3 J/cm 4.2 J/cm These findings indicated that Er:YAG laser may accelerate the regeneration process in periodontal tissues through enhancement of their proliferative and mobile activities. Additionally, the significance of galectin-7 in the Er:YAG laser-elicited benefits was demonstrated.
Sections du résumé
BACKGROUND/PURPOSE
OBJECTIVE
Among various dental lasers, the erbium-doped yttrium-aluminum-garnet (Er:YAG) laser has great potential for periodontal treatment including soft and hard tissue ablation with minimal thermal side effects under suitable energy densities and it has multiple effects on tissues for wound-healing benefits. In the present study, we sought to reveal the molecular mechanism underlying the impact of Er:YAG laser on PDL fibroblasts.
METHODS
METHODS
Cells were irradiated by a Er:YAG laser with various energy densities (3.6-6.3 J/cm
RESULTS
RESULTS
4.2 J/cm
CONCLUSION
CONCLUSIONS
These findings indicated that Er:YAG laser may accelerate the regeneration process in periodontal tissues through enhancement of their proliferative and mobile activities. Additionally, the significance of galectin-7 in the Er:YAG laser-elicited benefits was demonstrated.
Identifiants
pubmed: 32540310
pii: S0929-6646(20)30234-5
doi: 10.1016/j.jfma.2020.06.005
pii:
doi:
Substances chimiques
Galectins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
388-394Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have no conflicts of interest relevant to this article.