Soil protein as a potential antimicrobial agent against methicillin -resistant Staphylococcus aureus.
Antibacterial
Forest soil
MRSA
Natural products
Soil protein
Journal
Environmental research
ISSN: 1096-0953
Titre abrégé: Environ Res
Pays: Netherlands
ID NLM: 0147621
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
18
06
2019
revised:
04
02
2020
accepted:
27
02
2020
pubmed:
17
6
2020
medline:
21
11
2020
entrez:
17
6
2020
Statut:
ppublish
Résumé
Recently, the interest is increasing to find alternatives to replace the usage of antibiotics since their massive and improper usage enhance the antibiotic resistance in human pathogens. In this study, for the first time we showed that the soil proteins have very high antibacterial activity (98% of growth inhibition) against methicillin resistant Staphylococcus aureus (MRSA), one of the most threatening human pathogens. We found that the protein extract (C3) from the forest with past intensive management showed higher antibacterial activity than that of unmanaged forest. The MIC and IC
Identifiants
pubmed: 32540568
pii: S0013-9351(20)30213-9
doi: 10.1016/j.envres.2020.109320
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Soil
0
Methicillin
Q91FH1328A
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
109320Informations de copyright
Copyright © 2020. Published by Elsevier Inc.