Red blood cell alloimmunisation after platelet transfusion (excluding ABO blood group system).
Antigens, Surface
/ immunology
Blood Group Antigens
/ immunology
Blood Group Incompatibility
/ blood
Blood Grouping and Crossmatching
Blood Platelets
/ immunology
Cell-Derived Microparticles
/ immunology
Erythrocytes
/ immunology
Female
Humans
Inflammation
Isoantibodies
/ biosynthesis
Male
Platelet Transfusion
/ adverse effects
Pregnancy
Pregnancy Complications
/ blood
Rh Isoimmunization
/ blood
Rh-Hr Blood-Group System
/ immunology
Rho(D) Immune Globulin
/ biosynthesis
Alloimmunisation
Platelet
Prevention
Recipient
Red blood cell
Transfusion
Journal
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
ISSN: 1953-8022
Titre abrégé: Transfus Clin Biol
Pays: France
ID NLM: 9423846
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
17
03
2020
revised:
26
05
2020
accepted:
08
06
2020
pubmed:
17
6
2020
medline:
30
7
2021
entrez:
17
6
2020
Statut:
ppublish
Résumé
Red blood cell alloimmunisation after transfusion of red blood cell concentrates carries a risk for every recipient. This risk is particularly high for patients with conditions such as sickle cell disease. However, red blood cell alloimmunisation can also occur after platelet concentrate transfusion. All blood group systems other than ABO are affected, and there are several mechanisms responsible for this alloimmunisation. The practical implications of this are a need to match red blood cell concentrates in all alloimmunised patients and, in pregnant women, recongnition of the risk of developing haemolytic disease of the foetus and newborn. Several measures can be taken to prevent alloimmunisation: in the case of the D antigen, for example, anti-RhD immunoglobulins can be infused before transfusing platelet concentrates from an RhD-positive donor in a RhD-negative recipient.
Identifiants
pubmed: 32544526
pii: S1246-7820(20)30072-0
doi: 10.1016/j.tracli.2020.06.001
pii:
doi:
Substances chimiques
Antigens, Surface
0
Blood Group Antigens
0
Isoantibodies
0
RHO(D) antibody
0
Rh-Hr Blood-Group System
0
Rho(D) Immune Globulin
0
Rho(D) antigen
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
185-190Informations de copyright
Copyright © 2020 Société française de transfusion sanguine (SFTS). Published by Elsevier Masson SAS. All rights reserved.