Different BCS Class II Drug-Gelucire Solid Dispersions Prepared by Spray Congealing: Evaluation of Solid State Properties and In Vitro Performances.
Gelucire
carbamazepine
cinnarizine
microparticles
semicrystalline solid dispersions
spray chilling
spray cooling
tolbutamide
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
12 Jun 2020
12 Jun 2020
Historique:
received:
28
04
2020
revised:
05
06
2020
accepted:
10
06
2020
entrez:
18
6
2020
pubmed:
18
6
2020
medline:
18
6
2020
Statut:
epublish
Résumé
Delivery of poorly water soluble active pharmaceutical ingredients (APIs) by semi-crystalline solid dispersions prepared by spray congealing in form of microparticles (MPs) is an emerging method to increase their oral bioavailability. In this study, solid dispersions based on hydrophilic Gelucires
Identifiants
pubmed: 32545643
pii: pharmaceutics12060548
doi: 10.3390/pharmaceutics12060548
pmc: PMC7356387
pii:
doi:
Types de publication
Journal Article
Langues
eng
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