Clinical Features of Pseudoexfoliative Glaucoma in Treated Polish Patients.
epidemiology
glaucoma
pseudoexfoliation syndrome
pseudoexfoliative glaucoma
Journal
Clinical ophthalmology (Auckland, N.Z.)
ISSN: 1177-5467
Titre abrégé: Clin Ophthalmol
Pays: New Zealand
ID NLM: 101321512
Informations de publication
Date de publication:
2020
2020
Historique:
received:
20
11
2019
accepted:
06
04
2020
entrez:
18
6
2020
pubmed:
18
6
2020
medline:
18
6
2020
Statut:
epublish
Résumé
The aim of this study was to describe clinical characteristics of glaucomatous optic neuropathy in treated Polish patients with pseudoexfoliative glaucoma. In the course of the study, 348 eyes of 231 patients with pseudoexfoliative glaucoma. The patients involved in the study were treated in the Department of Diagnostic and Microsurgery of Glaucoma in Lublin between 2012 and 2019. The following parameters were assessed in the examination: visual acuity, slit-lamp biomicroscopy with evaluation of anterior segment of the eye, gonioscopic examination, stereoscopic fundus examination of the eye, intraocular pressure, visual field, and pachymetry. The mean age of all the patients was 73.16 years (SD±8.03). The mean age of women was 74.06 (SD±6.97), and the mean age of men was 71.8 (SD±8.51, p=0.006265). Women represented 37.93% (n=132) of the studied group, while men 62.07% (n=216). In the group of patients younger than 65 years of age, 27.9% were male and 15% female (p=0.0021). In the whole studied group, mean peak IOP was 29.25 mmHg with higher mean values in male patients (M vs F: 33.24 mmHg vs 26.86 mmHg; p=0.000). Peak values exceeding 30 mmHg were significantly more frequent in males (M vs F: 56.5% vs 31.9%; p=0.0000). Peak IOP never exceeding 21 mmHg was observed in 18.6% of the patients. The mean value of MD (Mean Deviation) was -12.85 dB in the whole group. The men were more likely to have more advanced glaucoma, according to MD (M vs F: -16.35 dB vs -11.13 dB; p=0.0000). Pseudoexfoliative glaucoma was more frequently observed in men with younger age, higher IOP, and more advanced glaucoma. Normotensive glaucoma was observed in 18.6% of the patients with pseudoexfoliative glaucoma.
Identifiants
pubmed: 32546945
doi: 10.2147/OPTH.S239371
pii: 239371
pmc: PMC7247722
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1373-1381Informations de copyright
© 2020 Łukasik et al.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
Références
Br J Ophthalmol. 2003 Nov;87(11):1321-3
pubmed: 14609823
Acta Ophthalmol Scand. 1999 Aug;77(4):371-5
pubmed: 10463402
Ophthalmic Genet. 2019 Aug;40(4):323-328
pubmed: 31322012
Acta Ophthalmol Scand. 2004 Feb;82(1):49-53
pubmed: 14982047
Acta Ophthalmol Suppl. 1962;Suppl 71:1-98
pubmed: 13993343
Graefes Arch Clin Exp Ophthalmol. 2012 Jul;250(7):1067-74
pubmed: 22134713
J Glaucoma. 2005 Dec;14(6):482-4
pubmed: 16276281
Ophthalmology. 2013 Aug;120(8):1551-8
pubmed: 23622877
EBioMedicine. 2015 May 30;2(7):765-9
pubmed: 26288849
Eye (Lond). 1989;3 ( Pt 6):747-53
pubmed: 2630357
Prog Brain Res. 2008;173:xi
pubmed: 18929096
J Glaucoma. 2009 Dec;18(9):684-8
pubmed: 20010248
Br J Ophthalmol. 1985 Feb;69(2):103-7
pubmed: 3966996
Acta Ophthalmol Suppl. 1988;184:112-5
pubmed: 2853906
Eur J Ophthalmol. 2004 Nov-Dec;14(6):495-500
pubmed: 15638098
Prog Retin Eye Res. 2003 May;22(3):253-75
pubmed: 12852486
Acta Ophthalmol Suppl. 1988;184:90-2
pubmed: 2853927
J Glaucoma. 2018 Jul;27 Suppl 1:S24-S28
pubmed: 29432335
Invest Ophthalmol Vis Sci. 1997 Sep;38(10):2008-15
pubmed: 9331264
Am J Ophthalmol. 2000 May;129(5):629-33
pubmed: 10844055
Hum Genomics. 2012 Oct 10;6:22
pubmed: 23157966
JAMA Ophthalmol. 2014 Dec;132(12):1439-45
pubmed: 25188364
Acta Ophthalmol (Copenh). 1991 Jun;69(3):273-80
pubmed: 1927307
Am J Ophthalmol. 1997 Nov;124(5):685-7
pubmed: 9372724
Nat Genet. 2015 Apr;47(4):387-92
pubmed: 25706626
Graefes Arch Clin Exp Ophthalmol. 2007 May;245(5):697-704
pubmed: 17028863
Cell Mol Life Sci. 2006 Oct;63(19-20):2304-16
pubmed: 16909208
Am J Ophthalmol. 1992 Oct 15;114(4):473-8
pubmed: 1415459
J Glaucoma. 1994 Summer;3(2):176-7
pubmed: 19920577
J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S12-4
pubmed: 25275897
Acta Ophthalmol Scand. 2007 Dec;85(8):822-7
pubmed: 18028119
Am J Ophthalmol. 2013 Jan;155(1):83-88.e1
pubmed: 23036566
Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):629-636
pubmed: 29392307
Arch Ophthalmol. 1982 Jul;100(7):1080-2
pubmed: 7092647
Science. 2007 Sep 7;317(5843):1397-400
pubmed: 17690259
Graefes Arch Clin Exp Ophthalmol. 2004 Sep;242(9):749-54
pubmed: 15052489
Exp Eye Res. 2017 Jan;154:88-103
pubmed: 27845061
Acta Ophthalmol Scand. 2007 Dec;85(8):828-31
pubmed: 17986290
Curr Opin Ophthalmol. 2015 Mar;26(2):82-9
pubmed: 25594764
Bull World Health Organ. 1995;73(1):115-21
pubmed: 7704921
Acta Ophthalmol (Copenh). 1971;49(2):334-43
pubmed: 5109796
J Glaucoma. 2006 Jun;15(3):229-37
pubmed: 16778646
Br J Ophthalmol. 2006 Mar;90(3):262-7
pubmed: 16488940
Am J Ophthalmol. 1994 Mar 15;117(3):333-6
pubmed: 8129006
Curr Opin Ophthalmol. 2010 Jan;21(1):25-34
pubmed: 19816175
Lancet. 2001 Feb 3;357(9253):359-60
pubmed: 11211000
Science. 2002 Feb 8;295(5557):1077-9
pubmed: 11834836
Mol Vis. 2013 Jul 12;19:1471-81
pubmed: 23869166
Mol Vis. 2015 Oct 13;21:1162-72
pubmed: 26539028
PLoS One. 2016 Jan 25;11(1):e0147540
pubmed: 26807726
Br J Ophthalmol. 2012 Sep;96(9):1180-4
pubmed: 22773091
Curr Diab Rep. 2016 Dec;16(12):124
pubmed: 27766584
Arch Ophthalmol. 1999 Oct;117(10):1319-24
pubmed: 10532440
Acta Ophthalmol Scand. 2001 Jun;79(3):283-5
pubmed: 11401639
Eur J Ophthalmol. 1996 Jan-Mar;6(1):26-9
pubmed: 8744847
J Glaucoma. 2003 Jun;12(3):193-7
pubmed: 12782834