Prevalence of Coronavirus Disease 2019 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
17 12 2020
Historique:
received: 13 05 2020
accepted: 11 06 2020
pubmed: 18 6 2020
medline: 26 3 2021
entrez: 18 6 2020
Statut: ppublish

Résumé

Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States. We established 2 high-throughput employee testing centers in Seattle, Washington, with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19. Between 12 March 2020 and 23 April 2020, 3477 symptomatic employees were tested for COVID-19 at 2 employee testing centers; 185 (5.3%) employees tested positive for COVID-19. The prevalence of SARS-CoV-2 was similar when comparing frontline HCWs (5.2%) with nonfrontline staff (5.5%). Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered. During the study period, we observed that the prevalence of positive SARS-CoV-2 tests among symptomatic HCWs was comparable to that of symptomatic nonfrontline staff. Reliable and rapid access to testing for employees is essential to preserve the health, safety, and availability of the healthcare workforce during this pandemic and to facilitate the rapid return of SARS-CoV-2-negative employees to work.

Sections du résumé

BACKGROUND
Healthcare workers (HCWs) who serve on the front lines of the coronavirus disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in some settings. Healthcare-acquired infection has been reported in similar epidemics, but there are limited data on the prevalence of COVID-19 among HCWs and their associated clinical outcomes in the United States.
METHODS
We established 2 high-throughput employee testing centers in Seattle, Washington, with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19.
RESULTS
Between 12 March 2020 and 23 April 2020, 3477 symptomatic employees were tested for COVID-19 at 2 employee testing centers; 185 (5.3%) employees tested positive for COVID-19. The prevalence of SARS-CoV-2 was similar when comparing frontline HCWs (5.2%) with nonfrontline staff (5.5%). Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered.
CONCLUSIONS
During the study period, we observed that the prevalence of positive SARS-CoV-2 tests among symptomatic HCWs was comparable to that of symptomatic nonfrontline staff. Reliable and rapid access to testing for employees is essential to preserve the health, safety, and availability of the healthcare workforce during this pandemic and to facilitate the rapid return of SARS-CoV-2-negative employees to work.

Identifiants

pubmed: 32548613
pii: 5858272
doi: 10.1093/cid/ciaa761
pmc: PMC7337651
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2702-2707

Subventions

Organisme : NIDDK NIH HHS
ID : T32 DK007742
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Références

J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
Clin Infect Dis. 2020 Nov 19;71(16):2218-2221
pubmed: 32179890
N Engl J Med. 2020 Mar 5;382(10):929-936
pubmed: 32004427
J Hosp Infect. 2011 Apr;77(4):332-7
pubmed: 21316802
JAMA. 2020 Jun 2;323(21):2133-2134
pubmed: 32259193
J Hosp Infect. 2020 May;105(1):100-101
pubmed: 32147406
N Engl J Med. 2020 May 21;382(21):2012-2022
pubmed: 32227758
JAMA. 2020 Apr 21;323(15):1439-1440
pubmed: 32163102
JAMA. 2020 May 26;323(20):2087-2089
pubmed: 32301962
Clin Infect Dis. 2020 Jul 28;71(15):858-860
pubmed: 32166318
BMJ. 2020 Mar 26;368:m1254
pubmed: 32217525
MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):477-481
pubmed: 32298247
N Engl J Med. 2020 Jun 4;382(23):2267-2268
pubmed: 32294342
Infect Control Hosp Epidemiol. 2020 Jun;41(6):745-746
pubmed: 32131906
Ann Intern Med. 2020 Jul 21;173(2):120-136
pubmed: 32369541
J Clin Microbiol. 2020 Jul 23;58(8):
pubmed: 32350048

Auteurs

Nandita S Mani (NS)

Department of Medicine, School of Medicine, University of Washington, Seattle, Washington, USA.

Jehan Z Budak (JZ)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Kristine F Lan (KF)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Chloe Bryson-Cahn (C)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Allison Zelikoff (A)

Population Health, Harborview Medical Center, Seattle, Washington, USA.

Gwendolyn E C Barker (GEC)

Allied Ambulatory Care Services, Harborview Medical Center, Seattle, Washington, USA.

Carolyn W Grant (CW)

Patient Care Services, University of Washington Medical Center-Northwest, Seattle, Washington, USA.

Kristi Hart (K)

Patient Care Services, University of Washington Medical Center-Northwest, Seattle, Washington, USA.

Carrie J Barbee (CJ)

Harborview Medical Center, Seattle, Washington, USA.

Marissa D Sandoval (MD)

Harborview Medical Center, Seattle, Washington, USA.

Christine L Dostal (CL)

Harborview Medical Center, Seattle, Washington, USA.

Maria Corcorran (M)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Hal M Ungerleider (HM)

Respiratory Therapy, University of Washington Medical Center-Northwest, Seattle, Washington, USA.

Jeff O Gates (JO)

Employee Health, University of Washington Medical Center-Northwest, Seattle, Washington, USA.

Svaya V Olin (SV)

Infection Prevention and Control, University of Washington Medical Center-Northwest, Seattle, Washington, USA.

Andrew Bryan (A)

Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA.

Noah G Hoffman (NG)

Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA.

Sara R Marquis (SR)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Michelle L Harvey (ML)

Clinical Trials Office, University of Washington, Seattle, Washington, USA.

Keri Nasenbeny (K)

Patient Care Services, University of Washington Medical Center, Seattle, Washington, USA.

Kathleen Mertens (K)

Primary Care and Population Health, Harborview Medical Center, Seattle, Washington, USA.

Lisa D Chew (LD)

Division of General Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.

Alexander L Greninger (AL)

Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Keith R Jerome (KR)

Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Paul S Pottinger (PS)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Timothy H Dellit (TH)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Catherine Liu (C)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Steven A Pergam (SA)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

Santiago Neme (S)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

John B Lynch (JB)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

H Nina Kim (HN)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Allergy and Infectious Diseases/Department of Medicine Research Collaboratory, University of Washington, Seattle, Washington, USA.

Seth A Cohen (SA)

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH