Exhaled Volatile Organic Compounds during Inflammation Induced by TNF-α in Ventilated Rats.

MCC-IMS TNF-α VOC anesthesia breath analysis inflammation multicapillary-column ion mobility spectrometry

Journal

Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790

Informations de publication

Date de publication:
15 Jun 2020
Historique:
received: 06 05 2020
revised: 09 06 2020
accepted: 11 06 2020
entrez: 19 6 2020
pubmed: 19 6 2020
medline: 19 6 2020
Statut: epublish

Résumé

Systemic inflammation alters the composition of exhaled breath, possibly helping clinicians diagnose conditions such as sepsis. We therefore evaluated changes in exhaled breath of rats given tumor necrosis factor-alpha (TNF-α). Thirty male Sprague-Dawley rats were randomly assigned to three groups (n = 10 each) with intravenous injections of normal saline (control), 200 µg·kg

Identifiants

pubmed: 32549262
pii: metabo10060245
doi: 10.3390/metabo10060245
pmc: PMC7345252
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Cancers (Basel). 2020 May 16;12(5):
pubmed: 32429446
Thorax. 2009 Sep;64(9):744-8
pubmed: 19158121
Genet Mol Res. 2012 Aug 16;11(3):2733-44
pubmed: 22869082
ACS Omega. 2018 May 31;3(5):5131-5140
pubmed: 30023907
PLoS One. 2014 Dec 09;9(12):e114555
pubmed: 25490772
J Breath Res. 2014 Mar;8(1):016006
pubmed: 24566204
Intensive Care Med. 1996 May;22(5):404-8
pubmed: 8796390
Br J Surg. 1994 Sep;81(9):1306-8
pubmed: 7953393
J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jan 15;881-882:76-82
pubmed: 22209594
J Breath Res. 2016 Mar 14;10(1):016016
pubmed: 26971584
J Breath Res. 2015 Mar 09;9(1):016007
pubmed: 25749729
J Leukoc Biol. 1997 May;61(5):559-66
pubmed: 9129204
Lung. 2017 Apr;195(2):247-254
pubmed: 28247041
Oncotarget. 2017 Dec 14;9(6):7204-7218
pubmed: 29467962
Anesthesiology. 2015 Jan;122(1):117-26
pubmed: 25170570
PLoS One. 2014 Apr 21;9(4):e95931
pubmed: 24752203
Science. 1986 Oct 24;234(4775):470-4
pubmed: 3764421
Mol Med Rep. 2018 Jan;17(1):179-185
pubmed: 29115434
PLoS Pathog. 2006 Feb;2(2):e4
pubmed: 16518473
Drug Des Devel Ther. 2015 Oct 12;9:5601-9
pubmed: 26491261
Cytokine Growth Factor Rev. 2014 Aug;25(4):453-72
pubmed: 25169849
Gut. 2016 Mar;65(3):400-7
pubmed: 25869737
Molecules. 2012 Jul 06;17(7):8159-73
pubmed: 22772811

Auteurs

Frederic W Albrecht (FW)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Felix Maurer (F)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Lukas M Müller-Wirtz (LM)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Michaela H Schwaiblmair (MH)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Tobias Hüppe (T)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Beate Wolf (B)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Daniel I Sessler (DI)

Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Thomas Volk (T)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Sascha Kreuer (S)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Tobias Fink (T)

CBR-Center of Breath Research, Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66421 Homburg/Saar, Germany.

Classifications MeSH