Long-term UVA exposure to the eye compromises memory and learning ability in mice via corticotropin-releasing hormone type 2 receptor.
Corticotropin-releasing hormone
Memory and learning ability
Microglia
Reactive oxygen species
Ultraviolet A
Urocortin 2
Journal
International journal of biological sciences
ISSN: 1449-2288
Titre abrégé: Int J Biol Sci
Pays: Australia
ID NLM: 101235568
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
03
2020
accepted:
10
04
2020
entrez:
19
6
2020
pubmed:
19
6
2020
medline:
16
11
2021
Statut:
epublish
Résumé
Long-term eye exposure to ultraviolet (UV)A can effect memory and learning ability. However, the underlying mechanism behind these effects remain unknown. In this study, we used HR-1 mice to study effects of long-term UVA eye irradiation. The eyes or dorsal skin of the mice were exposed to UVA at the dose of 110kj/m
Identifiants
pubmed: 32549763
doi: 10.7150/ijbs.45967
pii: ijbsv16p2170
pmc: PMC7294950
doi:
Substances chimiques
CRF receptor type 2
0
Reactive Oxygen Species
0
Receptors, Corticotropin-Releasing Hormone
0
Urocortins
0
Corticotropin-Releasing Hormone
9015-71-8
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2170-2179Informations de copyright
© The author(s).
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interest exists.
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