The protective roles of tea tree oil extracts in bovine mammary epithelial cells and polymorphonuclear leukocytes.
Bovine mammary epithelial cells
Mastitis
PMNL
Staphylococcus aureus
Tea tree oil
Journal
Journal of animal science and biotechnology
ISSN: 1674-9782
Titre abrégé: J Anim Sci Biotechnol
Pays: England
ID NLM: 101581293
Informations de publication
Date de publication:
2020
2020
Historique:
received:
19
09
2019
accepted:
01
05
2020
entrez:
19
6
2020
pubmed:
19
6
2020
medline:
19
6
2020
Statut:
epublish
Résumé
Tea tree oil (TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium and polymorphonuclear leukocytes (PMNL) can actively respond to bovine mastitis infection. However, regulatory effects of TTO extracts on the innate immune response of bovine mammary epithelial cells (BMECs) and PMNL remain not reported. Therefore, aim of the study was to evaluate the effects of TTO extracts on the mRNA levels of the genes involved in the innate immune response of BMECs and PMNL. Our results demonstrated that addition of 0.025% and 0.05% TTO increased the proliferation of BMECs, and significantly enhanced ( Our results indicate that use of TTO can relieve the BMECs pro-inflammatory response caused by
Sections du résumé
BACKGROUND
BACKGROUND
Tea tree oil (TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium and polymorphonuclear leukocytes (PMNL) can actively respond to bovine mastitis infection. However, regulatory effects of TTO extracts on the innate immune response of bovine mammary epithelial cells (BMECs) and PMNL remain not reported. Therefore, aim of the study was to evaluate the effects of TTO extracts on the mRNA levels of the genes involved in the innate immune response of BMECs and PMNL.
RESULTS
RESULTS
Our results demonstrated that addition of 0.025% and 0.05% TTO increased the proliferation of BMECs, and significantly enhanced (
CONCLUSIONS
CONCLUSIONS
Our results indicate that use of TTO can relieve the BMECs pro-inflammatory response caused by
Identifiants
pubmed: 32549980
doi: 10.1186/s40104-020-00468-9
pii: 468
pmc: PMC7294674
doi:
Types de publication
Journal Article
Langues
eng
Pagination
62Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they have no competing interests.
Références
Chest. 2000 Aug;118(2):503-8
pubmed: 10936147
Bioresour Technol. 2008 Dec;99(18):9004-8
pubmed: 18538563
J Dairy Sci. 2007 Jun;90 Suppl 1:E39-54
pubmed: 17517751
Planta Med. 2011 Jan;77(1):54-6
pubmed: 20560116
Front Immunol. 2014 Oct 07;5:493
pubmed: 25339959
Lett Appl Microbiol. 1998 Feb;26(2):118-22
pubmed: 9569693
J Mammary Gland Biol Neoplasia. 2011 Dec;16(4):383-407
pubmed: 21984469
Ann N Y Acad Sci. 2013 Apr;1283:67-74
pubmed: 23163321
J Dairy Sci. 1994 Feb;77(2):619-27
pubmed: 8182187
Int J Food Microbiol. 2007 Aug 15;118(1):15-9
pubmed: 17610974
J Dairy Sci. 2006 Jun;89(6):1877-95
pubmed: 16702252
Vet Q. 2002 Dec;24(4):181-98
pubmed: 12540135
J Dairy Sci. 2008 Jun;91(6):2205-14
pubmed: 18487643
J Dairy Sci. 2012 Oct;95(10):5720-9
pubmed: 22884338
Res Vet Sci. 2018 Feb;116:55-61
pubmed: 29275905
J Dairy Sci. 2000 Feb;83(2):278-84
pubmed: 10714861
Clin Microbiol Rev. 2006 Jan;19(1):50-62
pubmed: 16418522
J Dairy Sci. 2013 Jan;96(1):329-34
pubmed: 23127911
Vet Res. 2003 Sep-Oct;34(5):597-627
pubmed: 14556697
J Dairy Sci. 2016 May;99(5):3667-3674
pubmed: 26947297
J Dairy Sci. 2018 Nov;101(11):10089-10097
pubmed: 30146292
Curr Opin Pharmacol. 2011 Aug;11(4):397-403
pubmed: 21741310
Zentralbl Veterinarmed B. 1972 Aug;19(7):598-605
pubmed: 4486473
Nat Med. 2012 May;18(5):816-9
pubmed: 22522561
Genet Mol Res. 2013 Jul 30;12(3):2702-11
pubmed: 23979895
Microb Drug Resist. 2016 Dec;22(8):675-681
pubmed: 26990514
Lett Appl Microbiol. 2013 Jul;57(1):33-9
pubmed: 23581401
J Hosp Infect. 2006 Dec;64(4):313-25
pubmed: 17046102
Phytother Res. 2013 Mar;27(3):390-6
pubmed: 22619070
Phytomedicine. 1998 Dec;5(6):489-95
pubmed: 23196035
J Dairy Sci. 2015 Feb;98(2):918-26
pubmed: 25434342
BMC Genomics. 2010 Feb 25;11:138
pubmed: 20184744