The role of using different reference population in the prevalence of low BMD in the thalassemia patients.
DXA
Ethnicity
Normal control
Osteoporosis
Z-score
Journal
Journal of diabetes and metabolic disorders
ISSN: 2251-6581
Titre abrégé: J Diabetes Metab Disord
Pays: Switzerland
ID NLM: 101590741
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
06
04
2019
accepted:
15
10
2019
entrez:
19
6
2020
pubmed:
19
6
2020
medline:
19
6
2020
Statut:
epublish
Résumé
Prevalence of osteoporosis reported as high as 50% in thalassemia major patients. We compared bone density (BMD) of our patients with results of bone densitometry of participants of a national study, to find if BMD diagnosis is ethnicity sensitive or not. In 177 adult beta thalassemia major patients and 490 normal subjects of 20-39 y/o range, dual-energy X-ray absorptiometry of the spine and femur performed. Normal subjects participated in Iranian Multi-center Osteoporosis Study (IMOS). Mean and standard deviation of normal ones achieved and Z-score of patients re-calculated based on normal Iranians. As BMD of normal participants and patients performed by devices of different brands, analyses done based on calculated standard BMD of all participants. BMD of patients was significantly lower than normal participants ( We think in secondary osteoporosis, may be other cut-off points, especially according to BMD of normal population of that geographical region are needed.
Identifiants
pubmed: 32550194
doi: 10.1007/s40200-019-00455-6
pii: 455
pmc: PMC7270311
doi:
Types de publication
Journal Article
Langues
eng
Pagination
431-435Commentaires et corrections
Type : ErratumIn
Informations de copyright
© Springer Nature Switzerland AG 2019.
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