Malignancy risk for thyroid nodules larger than 4 cm and diagnostic reliability of ultrasound-guided FNAB results.
Thyroid nodule diameter
false negativity
fine needle aspiration biopsy
malignancy
Journal
Turkish journal of surgery
ISSN: 2564-6850
Titre abrégé: Turk J Surg
Pays: Turkey
ID NLM: 101704837
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
18
11
2017
accepted:
21
02
2018
entrez:
19
6
2020
pubmed:
1
3
2019
medline:
1
3
2019
Statut:
epublish
Résumé
Our aim in the present study was to investigate the relation between thyroid nodule diameter and malignancy, and the diagnostic accuracy of fine needle aspiration biopsy (FNAB) for thyroid nodules larger than 4 cm. Preoperative patient demographics such as age and gender, thyroid nodule diameter, FNAB results and postoperative pathology results were recorded. The relation between age, gender, thyroid nodule size of the patients and malignancy was examined. Also, the sensitivity, specificity, false negativity, false positivity and accuracy rates of FNBA of the patients whose thyroid nodule size was lower than 4 cm and the ones whose thyroid nodule size was higher than 4 cm were analyzed. There was no significant difference between males and females in terms of malignancy rate (p= 0.15). There was no significant relation between malignancy and patient age (p= 0.92). No significant difference was found between the group with thyroid nodule diameter of > 4 cm and the group thyroid with nodule diameter of <4 cm in terms of malignancy (p= 0.91). In the group with thyroid nodule diameter of > 4 cm, sensitivity, specificity, false negativity, false positivity, and accuracy rates of FNAB were 15%, 100%, 84%, 0%, and 70%, respectively. In the group with thyroid nodule diameter of <4 cm, sensitivity, specificity, false negativity, false positivity, and accuracy rates of FNAB were 53%, 100%, 46%, 0% and 80%, respectively. Our study put forward that thyroid nodule diameter is not the only predictor parameter whilst predicting malignancy. However, it was observed that FNAB sensitivity and false negativity were higher when the thyroid nodules with > 4 cm diameter were compared to the thyroid nodules with <4 cm diameter.
Identifiants
pubmed: 32550298
doi: 10.5578/turkjsurg.4029
pmc: PMC6791676
doi:
Types de publication
Journal Article
Langues
eng
Pagination
13-18Informations de copyright
Copyright © 2019, Turkish Surgical Society.
Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no conflicts of interest to declare.
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