The Project Baseline Health Study: a step towards a broader mission to map human health.

The Project Baseline Health Study (PBHS) was launched to map human health through a comprehensive understanding of both the health of an individual and how it relates to the broader population. The study will contribute to the creation of a biomedical information system that accounts for the highly complex interplay of biological, behavioral, environmental, and social systems. The PBHS is a prospective, multicenter, longitudinal cohort study that aims to enroll thousands of participants with diverse backgrounds who are representative of the entire health spectrum. Enrolled participants will be evaluated serially using clinical, molecular, imaging, sensor, self-reported, behavioral, psychological, environmental, and other health-related measurements. An initial deeply phenotyped cohort will inform the development of a large, expanded virtual cohort. The PBHS will contribute to precision health and medicine by integrating state of the art testing, longitudinal monitoring and participant engagement, and by contributing to the development of an improved platform for data sharing and analysis.

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© The Author(s) 2020.

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Competing interestsK.A. received research funding from Verily Inc. for work at Duke Clinical and Translational Science Institute. R.C. and J.H. are employed or have a leadership role at at Google Health. R.C. is also a Board member, Cytokinetics. M.D. receives research funding from Celgene, Abbvie, United Therapeutics, Varian, Genzyme, Novartis, Verily Inc., and consults or receives honoraria from Astra Zeneca, Bristol Myer Squibb. A.H. receives research funding from American Regent, AstraZeneca, Merck, Novartis, Verily Inc., and consults for Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Boston Scientific, Merck, Novartis, and Sanofi. C.L. has the following engagements Shareholder and Advisory Board, whiterabbit.ai; Shareholder, Nines.ai; Advisory Board, Nines.ai; Shareholder, GalileoCDS, Inc.; Advisory Board, GalileoCDS, Inc; Shareholder and Board of Directors Bunker Hill, Inc.; Research Grant, GE Healthcare; Departmental Research Grant, Koninklijke Philips NV; Departmental Research Grant, Siemens AG; School of Medicine Research Grant, Google, Inc.; Travel Grant, Canon Medical Systems Corp; Travel Grant, Siemens Healthineers. S.S.G. is a consultant or receives funding from several companies that work in the healthcare space although none of these companies are directly involved in the current work. K.W.M.’s financial disclosure can be viewed at http://med.stanford.edu/profiles/kenneth-mahaffey. W.J.M., J.M., D.M., and S.S. are employed, have a leadership role, or receive equity from Verily Inc. J.M. is also a Board Member, Danaher. L.K.N. received research grant support from Verily Inc.