The Role of Highly Active Antiretroviral Therapy (HAART) on Interleukin 17A (IL-17A) in Normotensive and Preeclamptic Black South African Women.


Journal

Infectious diseases in obstetrics and gynecology
ISSN: 1098-0997
Titre abrégé: Infect Dis Obstet Gynecol
Pays: Egypt
ID NLM: 9318481

Informations de publication

Date de publication:
2020
Historique:
received: 02 02 2020
revised: 27 04 2020
accepted: 01 05 2020
entrez: 20 6 2020
pubmed: 20 6 2020
medline: 16 7 2021
Statut: epublish

Résumé

Interleukin 17A has been implicated in the pathophysiology of both human immune deficiency virus and preeclampsia. This study evaluated serum levels of IL-17A based on pregnancy type, gestational age, HIV status, and duration of HAART. Pregnancy type: the levels of IL-17A were increased in PE compared to N ( The study demonstrates that IL-17A is involved in the pathophysiology of PE and that in the presence of HIV infection, chronic HAART administration predisposes women to the development of EOPE.

Identifiants

pubmed: 32550763
doi: 10.1155/2020/3417632
pmc: PMC7277031
doi:

Substances chimiques

IL17A protein, human 0
Interleukin-17 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3417632

Informations de copyright

Copyright © 2020 Wendy N. Phoswa et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Wendy N Phoswa (WN)

Discipline of Obstetrics and Gynecology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

Thajasvarie Naicker (T)

Optics and Imaging Centre, University of KwaZulu-Natal, Durban, South Africa.

Veron Ramsuran (V)

KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.

Jagidesa Moodley (J)

Women's Health and HIV Research Group, University of KwaZulu-Natal, Durban, South Africa.

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Classifications MeSH