Drug discovery and chemical probing in

Animals Disease Models, Animal Drosophila / drug effects Drug Discovery Drug Evaluation, Preclinical
Drosophila criblage de composés drug discovery drug screens découverte de médicaments maladies orphelines modèles animaux orphan disease pathway probing polycystic kidney disease polykystose rénale sondage des sentiers whole-animal models

Journal

Genome
ISSN: 1480-3321
Titre abrégé: Genome
Pays: Canada
ID NLM: 8704544

Informations de publication

Date de publication:
Feb 2021
Historique:
pubmed: 20 6 2020
medline: 15 12 2021
entrez: 20 6 2020
Statut: ppublish

Résumé

Flies are increasingly utilized in drug discovery and chemical probing in vivo, which are novel technologies complementary to genetic probing in fundamental biological studies. Excellent genetic conservation, small size, short generation time, and over one hundred years of genetics make

Identifiants

DOI: 10.1139/gen-2020-0037 PMID: 32551911
pubmed: 32551911
doi: 10.1139/gen-2020-0037
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

147-159

Auteurs

Cassandra Millet-Boureima (C)

Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.
Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.

Susannah Selber-Hnatiw (S)

Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.
Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.

Chiara Gamberi (C)

Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.
Biology Department, Concordia University, Montreal, QC H4B 1R6, Canada.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Drug discovery and chemical probing in
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Drug discovery and chemical probing in
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drug discovery and chemical probing in
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Drug discovery and chemical probing in
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Drug discovery and chemical probing in