Optical coherence tomography in the evaluation of retinitis pigmentosa.
Optical coherence tomography
cystoid macular edema
optical coherence tomography angiography
retinal thickness
retinitis pigmentosa
Journal
Ophthalmic genetics
ISSN: 1744-5094
Titre abrégé: Ophthalmic Genet
Pays: England
ID NLM: 9436057
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
pubmed:
20
6
2020
medline:
22
6
2021
entrez:
20
6
2020
Statut:
ppublish
Résumé
Optical coherence tomography (OCT) is a non-invasive imaging test that provides easily obtainable and highly reproducible cross-sectional images of the retina. Improved modalities of the OCT that are capable of providing high quality images of not only the retina, but also the deeper structures and vasculature have been developed, including swept-source OCTs and OCT angiography. Review. The use of OCT in the monitoring of retinitis pigmentosa has been well described and numerous signs of disease progression have been studied. Notably among them are the detection of changes to retinal thickness, the ellipsoid zone, the vasculature on OCT angiography, and cystoid macular edema. In this review, we discuss the multiple applications of OCT as a tool in the monitoring of retinitis pigmentosa and its potential use as an outcome measurement in current and future therapeutic endeavors.
Sections du résumé
BACKGROUND
Optical coherence tomography (OCT) is a non-invasive imaging test that provides easily obtainable and highly reproducible cross-sectional images of the retina. Improved modalities of the OCT that are capable of providing high quality images of not only the retina, but also the deeper structures and vasculature have been developed, including swept-source OCTs and OCT angiography.
MATERIALS AND METHODS
Review.
RESULTS
The use of OCT in the monitoring of retinitis pigmentosa has been well described and numerous signs of disease progression have been studied. Notably among them are the detection of changes to retinal thickness, the ellipsoid zone, the vasculature on OCT angiography, and cystoid macular edema.
CONCLUSION
In this review, we discuss the multiple applications of OCT as a tool in the monitoring of retinitis pigmentosa and its potential use as an outcome measurement in current and future therapeutic endeavors.
Identifiants
pubmed: 32552399
doi: 10.1080/13816810.2020.1780619
pmc: PMC9362879
mid: NIHMS1606984
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
413-419Subventions
Organisme : NIA NIH HHS
ID : R21 AG050437
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY018213
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY026682
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA013696
Pays : United States
Organisme : NEI NIH HHS
ID : R24 EY028758
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY024698
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY019007
Pays : United States
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