[Analysis of the Irregular Antibodies of the Patients and Its Clinical Significance].

To retrospectively analyze the identification results of irregular antibodies, to clarify the distribution features and to explore the relation of alloantibodies and autoantibodies with the immunized history of patients and disease kinds. 49 820 patients who applied for red blood transfusion during Sep 1st 2017 to Sep 1st 2018 were selected. All the specimens were screened for the antibody by microcolumn gel antiglobulin technique, which then were identified for irregular antibody. Antibodies were found in 861 (1.73%) of all 49 820 transfused samples. The alloimmunization history of the patients with antibodies was significantly different between male and female (χ The most important factor that results in antibody-screening positive is alloantibody, in which anti-E antibody from Rh blood group system in most common. 患者不规则抗体鉴定结果分析及其临床意义. 回顾性分析患者的不规则抗体鉴定结果、明确其分布特点，并探讨同种抗体、自身抗体与患者免疫史、疾病种类的关系. 选取2017年9月1日-2018年9月1日于本院申请输注红细胞的患者49 820例，采用抗人球蛋白微柱凝胶卡进行不规则抗体筛查，阳性标本均行进一步抗体鉴定. 49 820例患者标本中不规则抗体筛查阳性861例，阳性率为1.73%；产生不规则抗体的患者中，女性与男性接受异体免疫史的差异有显著统计学意义(χ 导致抗筛阳性的主要因素为同种抗体，其中Rh血型系统的抗-E抗体最多见.