Asymptomatic Right Atrial Thrombosis After Acute Lymphoblastic Leukemia Treatment.
Adolescent
Anticoagulants
/ therapeutic use
Antineoplastic Combined Chemotherapy Protocols
/ adverse effects
Child
Child, Preschool
Female
Heart Atria
/ drug effects
Heparin, Low-Molecular-Weight
/ therapeutic use
Humans
Incidence
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/ complications
Retrospective Studies
Thrombosis
/ drug therapy
Journal
Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928
Informations de publication
Date de publication:
01 05 2021
01 05 2021
Historique:
received:
14
02
2020
accepted:
28
04
2020
pubmed:
20
6
2020
medline:
15
5
2021
entrez:
20
6
2020
Statut:
ppublish
Résumé
Right atrial thrombosis is a rare, but potentially serious complication of acute lymphoblastic leukemia treatment. We conducted a retrospective multicenter study to assess the incidence, treatment, and outcome of asymptomatic right atrial thrombosis detected at routine echocardiography of children after acute lymphoblastic leukemia treatment in the Nordic and Baltic countries. Eleven (2.7%, 95% confidence interval, 1.4-4.9) of 406 patients had asymptomatic right atrial thrombosis, ranging from 10 to 25 mm at detection. Three patients were treated with anticoagulation. None of the thromboses affected cardiac function, and they showed neither sign of progress nor spontaneous or treatment-related regress at follow-up.
Identifiants
pubmed: 32555028
pii: 00043426-202105000-00035
doi: 10.1097/MPH.0000000000001848
doi:
Substances chimiques
Anticoagulants
0
Heparin, Low-Molecular-Weight
0
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e564-e566Informations de copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
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