A three-arm randomized study to compare sexual functions and fertility indices following open mesh hernioplasty (OMH), laparoscopic totally extra peritoneal (TEP) and transabdominal preperitoneal (TAPP) repair of groin hernia.


Journal

Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653

Informations de publication

Date de publication:
06 2021
Historique:
received: 06 04 2020
accepted: 09 06 2020
pubmed: 20 6 2020
medline: 30 9 2021
entrez: 20 6 2020
Statut: ppublish

Résumé

With evolving technology, the focus of groin hernia repair has shifted to sexual function and fertility outcomes. This three-arm randomized study was conducted in tertiary care hospital from 1st July 2017 to 30th March 2019. Consecutive patients of groin hernia were randomized into 3 groups, TAPP (Group 1), TEP (Group 2), and OMH (Group 3). Demographic profile and hernia characteristics were assessed preoperatively. Sexual functions (using BMSFI) and fertility (using surrogate fertility indices, viz., semen analysis and anti-sperm antibodies (ASA)) were assessed preoperatively at 3 months after the surgery. A total of 121 patients were included in the study with 41 patients in TAPP (Group 1) and 40 each in TEP (Group 2) and OMH (Group3) group. All the 3 groups were comparable in terms of demographic profile, hernia characteristics, intra-operative and early post-operative outcomes. Significant improvement was found in most of the domains of BMSFI score in the study population (p value < 0.001) with no intergroup difference. There was significant increase of anti-sperm antibody level in OMH group as compared to TAPP and TEP (p = 0.001), however, the levels were within normal limit. In conclusion, this study has shown that inguinal hernia repair whether open or laparoscopic (TEP or TAPP) leads on to improvement in sexual functions and fertility indices and can have a significant impact on pre-op counseling of the patient in terms of choice of repair, depending on the available expertise in a given center.

Sections du résumé

BACKGROUND
With evolving technology, the focus of groin hernia repair has shifted to sexual function and fertility outcomes.
METHODS
This three-arm randomized study was conducted in tertiary care hospital from 1st July 2017 to 30th March 2019. Consecutive patients of groin hernia were randomized into 3 groups, TAPP (Group 1), TEP (Group 2), and OMH (Group 3). Demographic profile and hernia characteristics were assessed preoperatively. Sexual functions (using BMSFI) and fertility (using surrogate fertility indices, viz., semen analysis and anti-sperm antibodies (ASA)) were assessed preoperatively at 3 months after the surgery.
RESULTS
A total of 121 patients were included in the study with 41 patients in TAPP (Group 1) and 40 each in TEP (Group 2) and OMH (Group3) group. All the 3 groups were comparable in terms of demographic profile, hernia characteristics, intra-operative and early post-operative outcomes. Significant improvement was found in most of the domains of BMSFI score in the study population (p value < 0.001) with no intergroup difference. There was significant increase of anti-sperm antibody level in OMH group as compared to TAPP and TEP (p = 0.001), however, the levels were within normal limit.
CONCLUSIONS
In conclusion, this study has shown that inguinal hernia repair whether open or laparoscopic (TEP or TAPP) leads on to improvement in sexual functions and fertility indices and can have a significant impact on pre-op counseling of the patient in terms of choice of repair, depending on the available expertise in a given center.

Identifiants

pubmed: 32556769
doi: 10.1007/s00464-020-07697-z
pii: 10.1007/s00464-020-07697-z
doi:

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

3077-3084

Références

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Auteurs

Shardool Gupta (S)

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Asuri Krishna (A)

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India. dr.asurikrishna@gmail.com.

Ankur Goyal (A)

Department of Radio Diagnosis, All India Institute of Medical Sciences, New Delhi, India.

Atin Kumar (A)

Department of Radio Diagnosis, All India Institute of Medical Sciences, New Delhi, India.

Pradeep Chaturvedi (P)

Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi, India.

Rajesh Sagar (R)

Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.

Rashmi Ramachandran (R)

Department of Anesthesiology, All India Institute of Medical Sciences, New Delhi, India.

Om Prakash (O)

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Subodh Kumar (S)

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

V Seenu (V)

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Virinder Bansal (V)

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

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