Combining Appleby with RAMPS - Laparoscopic Radical Antegrade Modular Pancreatosplenectomy with Celiac Trunk Resection.


Journal

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
ISSN: 1873-4626
Titre abrégé: J Gastrointest Surg
Pays: United States
ID NLM: 9706084

Informations de publication

Date de publication:
11 2020
Historique:
received: 21 05 2020
accepted: 02 06 2020
pubmed: 20 6 2020
medline: 15 4 2021
entrez: 20 6 2020
Statut: ppublish

Résumé

Radical Antegrade Modular Pancreatosplenectomy (RAMPS) minimizes the risk of a positive retroperitoneal margin and maximizes lymph node harvest in distal pancreatic cancers.1-7 In those with celiac trunk involvement, resection of the celiac trunk (modified Appleby procedure) is a surgical option in which postoperative liver perfusion relies on blood flow via superior mesenteric artery (SMA) and gastroduodenal artery (GDA).8, 9 PATIENT: A 66-year-old male was diagnosed with a 3.8 × 2.5 cm pancreatic body adenocarcinoma abutting the celiac trunk. Neoadjuvant FOLFIRINOX was initiated with a uniquely good response. Prior to surgery, a novel preoperative 3D simulation technique accounting for organ displacement during pneumoperitoneum with the goal of optimizing port placement and surgical decision making was employed. At surgery, a RAMPS procedure was performed with the renal vessels and adrenal gland being dissected first (reversed from typical open approach). Following dissection along the SMA towards the celiac axis, desmoplastic reaction enveloping the celiac trunk necessitated its resection. Arterial liver perfusion was confirmed with intraoperative ultrasound. L-RAMPS and modified Appleby procedure is a curative option for patients with distal pancreatic cancers that invade the celiac trunk and in whom the tumor biology is well controlled. A preplanned approach with 3D reconstruction accounting for organ displacement due to pneumoperitoneum optimizes surgical decision making and port placement for visual alignment caudally along the SMA.

Sections du résumé

BACKGROUND
Radical Antegrade Modular Pancreatosplenectomy (RAMPS) minimizes the risk of a positive retroperitoneal margin and maximizes lymph node harvest in distal pancreatic cancers.1-7 In those with celiac trunk involvement, resection of the celiac trunk (modified Appleby procedure) is a surgical option in which postoperative liver perfusion relies on blood flow via superior mesenteric artery (SMA) and gastroduodenal artery (GDA).8, 9 PATIENT: A 66-year-old male was diagnosed with a 3.8 × 2.5 cm pancreatic body adenocarcinoma abutting the celiac trunk. Neoadjuvant FOLFIRINOX was initiated with a uniquely good response.
TECHNIQUE
Prior to surgery, a novel preoperative 3D simulation technique accounting for organ displacement during pneumoperitoneum with the goal of optimizing port placement and surgical decision making was employed. At surgery, a RAMPS procedure was performed with the renal vessels and adrenal gland being dissected first (reversed from typical open approach). Following dissection along the SMA towards the celiac axis, desmoplastic reaction enveloping the celiac trunk necessitated its resection. Arterial liver perfusion was confirmed with intraoperative ultrasound.
CONCLUSION
L-RAMPS and modified Appleby procedure is a curative option for patients with distal pancreatic cancers that invade the celiac trunk and in whom the tumor biology is well controlled. A preplanned approach with 3D reconstruction accounting for organ displacement due to pneumoperitoneum optimizes surgical decision making and port placement for visual alignment caudally along the SMA.

Identifiants

pubmed: 32557017
doi: 10.1007/s11605-020-04686-4
pii: 10.1007/s11605-020-04686-4
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2700-2701

Références

Strasberg SM, Drebin JA, Linehan D. Radical antegrade modular pancreatosplenectomy. Surgery. 2003;133(5):521-527.
doi: 10.1067/msy.2003.146
Strasberg SM, Fields R. Left-sided pancreatic cancer: distal pancreatectomy and its variants: radical antegrade modular pancreatosplenectomy and distal pancreatectomy with celiac axis resection. Cancer J. 2012;18(6):562-570.
doi: 10.1097/PPO.0b013e31827596c5
Strasberg SM, Linehan DC, Hawkins WG. Radical antegrade modular pancreatosplenectomy procedure for adenocarcinoma of the body and tail of the pancreas: ability to obtain negative tangential margins. J Am Coll Surg. 2007;204(2):244-249.
doi: 10.1016/j.jamcollsurg.2006.11.002
Cao F, Li J, Li A, Li F. Radical antegrade modular pancreatosplenectomy versus standard procedure in the treatment of left-sided pancreatic cancer: A systemic review and meta-analysis. BMC Surg. 2017;17(1):67.
doi: 10.1186/s12893-017-0259-1
Zhou Y, Shi B, Wu L, Si X. A systematic review of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of the pancreas. HPB (Oxford). 2017;19(1):10-15.
doi: 10.1016/j.hpb.2016.07.014
Goumard C, Ogiso S, Okuno M, et al. Tips and tricks of splenic vessel preservation during laparoscopic distal pancreatectomy. Surg Endosc. 2018;32(4):2149-2150.
doi: 10.1007/s00464-017-5744-1
Joechle K, Conrad C. Cost-effectiveness of minimally invasive pancreatic resection. J Hepatobiliary Pancreat Sci. 2018;25(6):291-298.
doi: 10.1002/jhbp.558
Appleby LH. The coeliac axis in the expansion of the operation for gastric carcinoma. Cancer. 1953;6(4):704-707.
doi: 10.1002/1097-0142(195307)6:4<704::AID-CNCR2820060410>3.0.CO;2-P
Klompmaker S, Peters NA, van Hilst J, et al. Outcomes and Risk Score for Distal Pancreatectomy with Celiac Axis Resection (DP-CAR): An International Multicenter Analysis. Ann Surg Oncol. 2019;26(3):772-781.
doi: 10.1245/s10434-018-07101-0

Auteurs

Omid Salehi (O)

Department of Surgery, St Elizabeth's Medical Center, Tufts University School of Medicine, 11 Nevins St., Suite 201, Boston, MA, 02135, USA.

Eduardo A Vega (EA)

Department of Surgery, St Elizabeth's Medical Center, Tufts University School of Medicine, 11 Nevins St., Suite 201, Boston, MA, 02135, USA.

Onur C Kutlu (OC)

Department of Surgery, University of Miami Health System, Miller School of Medicine, Miami, FL, USA.

Sylvia V Alarcon Velasco (SV)

Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Sandeep Krishnan (S)

Department of Gastroenterology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA.

David Ricklan (D)

Department of Pathology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA.

Olga Kozyreva (O)

Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Claudius Conrad (C)

Department of Surgery, St Elizabeth's Medical Center, Tufts University School of Medicine, 11 Nevins St., Suite 201, Boston, MA, 02135, USA. claudius.conrad@steward.org.

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