Detection of aortic prosthetic graft infection with
Adult
Aged
Aorta, Thoracic
Aortic Diseases
/ diagnostic imaging
Blood Vessel Prosthesis
/ adverse effects
Female
Fluorodeoxyglucose F18
Humans
Male
Middle Aged
Positron Emission Tomography Computed Tomography
Predictive Value of Tests
Prospective Studies
Prosthesis-Related Infections
/ diagnostic imaging
Radiopharmaceuticals
Reproducibility of Results
Young Adult
18F-FDG
PET/CT
antibiotic
diagnostic concordance
infection
prosthetic vascular graft
Journal
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
received:
19
02
2020
accepted:
28
05
2020
pubmed:
20
6
2020
medline:
8
2
2022
entrez:
20
6
2020
Statut:
ppublish
Résumé
The aim of this study was to investigate the diagnostic yield of Patients suspected clinically of having thoracic-AGI were prospectively recruited. Consensus MAGIC criteria for AGI were compared to findings on FDG PET imaging. MAGIC criteria were verified against clinical/surgical, radiological, and microbiological/laboratory predefined major and minor parameters. FDG images were interpreted using a semiquantitative visual grading score (VGS, abnormal ≥ 3), focal uptake and quantitative maximum standard FDG uptake value (SUV Of 35 patients suspected of having thoracic-AGI, MAGIC diagnostic criteria were positive for AGI in 25 patients (71%) and negative in 10 (29%). FDG PET imaging was abnormal in 27 patients (77%). Abnormal and normal FDG imaging findings were concordant with MAGIC criteria in 31 patients (88.6%). In 4 patients, FDG imaging results were discordant with MAGIC criteria. By ROC analysis, optimal FDG cut-off values for detecting AGI by MAGIC were ≥ 3 for VGS, ≥ 7.3 for SUV FDG PET/CT imaging, using (semi-)quantitative imaging parameters, showed high concordance with expert consensus MAGIC criteria for AGI. These data suggest a potential complementary role of quantitative FDG/CT imaging, not only to detect AGI, but also to monitor response to antibiotic treatment.
Identifiants
pubmed: 32557154
doi: 10.1007/s12350-020-02227-9
pii: 10.1007/s12350-020-02227-9
doi:
Substances chimiques
Radiopharmaceuticals
0
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1005-1016Commentaires et corrections
Type : CommentIn
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