Multisystemic manifestations of IgA vasculitis.
Complications
Henoch-Schönlein Purpura
IgA vasculitis
Vasculitis
Journal
Clinical rheumatology
ISSN: 1434-9949
Titre abrégé: Clin Rheumatol
Pays: Germany
ID NLM: 8211469
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
19
03
2020
accepted:
11
05
2020
revised:
07
05
2020
pubmed:
20
6
2020
medline:
15
5
2021
entrez:
20
6
2020
Statut:
ppublish
Résumé
Immunoglobulin A vasculitis (IgAV), also known as Henoch-Schönlein Purpura, is one of the most common kind of systemic vasculitis in children, and due to the involvement of small blood vessels throughout the body, this disease can cause a variety of symptoms in different organs. Our aim was to review the data on various systemic manifestations of IgAV. A research of the literature was performed in PubMed database, utilizing the MeSH terms "IgA vasculitis" and "Henoch Schönlein Purpura". According to the predetermined structure of the manuscript, we extracted and sorted out the relevant data. Clinically, almost all the patients will present with palpable skin purpura, together with arthritis, gastrointestinal tract involvement, or kidney damage. Other rare systemic manifestations include neurological symptoms, scrotal involvement, and cardiopulmonary disease. When uncommon complications occur, patients may be misdiagnosed as other diseases, thus delaying treatment. Although the course of IgAV is mostly self-limited, misdiagnosis can also lead to a poor prognosis. A comprehensive awareness to the clinical manifestations of IgAV is the necessary prerequisite for its timely diagnosis. Prompt diagnosis and adequate treatment are essential for optimal results.
Identifiants
pubmed: 32557258
doi: 10.1007/s10067-020-05166-5
pii: 10.1007/s10067-020-05166-5
doi:
Substances chimiques
Immunoglobulin A
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
43-52Subventions
Organisme : Natural Science Foundation of Beijing Municipality (CN)
ID : 7172076
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