Hypermetabolism and Coronavirus Disease 2019.
calorimetry
nutrition assessment
pulmonary disease
Journal
JPEN. Journal of parenteral and enteral nutrition
ISSN: 1941-2444
Titre abrégé: JPEN J Parenter Enteral Nutr
Pays: United States
ID NLM: 7804134
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
12
05
2020
accepted:
17
06
2020
pubmed:
20
6
2020
medline:
29
12
2020
entrez:
20
6
2020
Statut:
ppublish
Résumé
Hypermetabolism has been described in stress states such as trauma, sepsis, acute respiratory distress syndrome, and severe burn injuries. We hypothesize that patients with Coronavirus disease 2019 (COVID-19) may develop a hypermetabolic state, which may be a major contributing factor to the extraordinary ventilatory and oxygenation demands in patients with COVID-19. Resting energy expenditure (REE), carbon dioxide production (VCO The median measured REE was 4044 kcal/d, which was 235.7% ± 51.7% of predicted. The median VCO Critically ill patients with COVID-19 are in an extreme hypermetabolic state. This may explain the high failure rates for mechanical ventilation for these patients and highlights the potential need for increased nutrition requirements for such patients.
Sections du résumé
BACKGROUND
Hypermetabolism has been described in stress states such as trauma, sepsis, acute respiratory distress syndrome, and severe burn injuries. We hypothesize that patients with Coronavirus disease 2019 (COVID-19) may develop a hypermetabolic state, which may be a major contributing factor to the extraordinary ventilatory and oxygenation demands in patients with COVID-19.
METHOD
Resting energy expenditure (REE), carbon dioxide production (VCO
RESULTS
The median measured REE was 4044 kcal/d, which was 235.7% ± 51.7% of predicted. The median VCO
CONCLUSION
Critically ill patients with COVID-19 are in an extreme hypermetabolic state. This may explain the high failure rates for mechanical ventilation for these patients and highlights the potential need for increased nutrition requirements for such patients.
Identifiants
pubmed: 32559309
doi: 10.1002/jpen.1948
pmc: PMC7323185
doi:
Substances chimiques
Carbon Dioxide
142M471B3J
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1234-1236Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 American Society for Parenteral and Enteral Nutrition.
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