Parkinson's Disease Multimodal Complex Treatment (PD-MCT): Analysis of Therapeutic Effects and Predictors for Improvement.
MDS-UPDRS Part III
Parkinson’s disease
motor complications
motor symptoms
multimodal complex treatment
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
16 Jun 2020
16 Jun 2020
Historique:
received:
11
05
2020
revised:
10
06
2020
accepted:
12
06
2020
entrez:
21
6
2020
pubmed:
21
6
2020
medline:
21
6
2020
Statut:
epublish
Résumé
Parkinson's disease Multimodal Complex Treatment (PD-MCT) is a multidisciplinary inpatient treatment approach that has been demonstrated to improve motor function and quality of life in patients with Parkinson's disease (PD). In this study, we assessed the efficacy of PD-MCT and calculated predictors for improvement. We performed a prospective analysis in a non-randomized, open-label observational patient cohort. Study examinations were done at baseline (BL), at discharge after two-weeks of inpatient treatment (DC) and at a six-week follow-up examination (FU). Besides Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III as a primary outcome, motor performance was measured by the Timed Up-and-Go (TUG), the Berg Balance Scale (BBS) and the Perdue Pegboard Test (PPT). Until DC, motor performance improved significantly in several parameters and was largely maintained until FU (MDS-UPDRS III BL-to-DC: -4.7 ± 1.2 (SE)
Identifiants
pubmed: 32560079
pii: jcm9061874
doi: 10.3390/jcm9061874
pmc: PMC7356837
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Deutsche Parkinson Vereinigung Bundesverband
ID : 33.17-92907
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