Pomegranate Mesocarp against Colitis-Induced Visceral Pain in Rats: Effects of a Decoction and Its Fractions.
DNBS
IBDs
IBS
chronic visceral pain
colitis
ellagitannins
polysaccharides
punicalagin
rats
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
17 Jun 2020
17 Jun 2020
Historique:
received:
30
05
2020
revised:
15
06
2020
accepted:
15
06
2020
entrez:
21
6
2020
pubmed:
21
6
2020
medline:
17
2
2021
Statut:
epublish
Résumé
The management of chronic visceral pain related to Inflammatory Bowel Diseases or Irritable Bowel Syndrome is still a clinical problem and new therapeutic strategies continue to be investigated. In the present study, the efficacy of a pomegranate decoction and of its polysaccharide and ellagitannin components in preventing the development of colitis-induced abdominal pain in rats was evaluated. After colitis induction by 2,4-dinitrobenzenesulfonic acid (DNBS), the pomegranate decoction (300 mg kg
Identifiants
pubmed: 32560291
pii: ijms21124304
doi: 10.3390/ijms21124304
pmc: PMC7353021
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Biomarkers
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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