Intelligent therapeutic decision support for 30 days readmission of diabetic patients with different comorbidities.
30 days readmission
Bayesian network
Comorbidity
Diabetes
Medication therapy
Random forest
Journal
Journal of biomedical informatics
ISSN: 1532-0480
Titre abrégé: J Biomed Inform
Pays: United States
ID NLM: 100970413
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
18
02
2020
revised:
10
06
2020
accepted:
12
06
2020
pubmed:
21
6
2020
medline:
29
7
2021
entrez:
21
6
2020
Statut:
ppublish
Résumé
The significance of medication therapy in managing comorbid diabetes is vital for maintaining the overall wellness of patients and reducing the cost of healthcare. Thus, using appropriate medication or medication combinations will be necessary for improved person-centred care and reduce complications associated with diagnosis and treatment. This study explains an intelligent decision support framework for managing 30 days unplanned readmission (30_URD) of comorbid diabetes using the Random Forest (RF) algorithm and Bayesian Network (BN) model. After the analysis of the medical records of 101,756 de-identified diabetic patients treated with 21 medications for 28 comorbidity combinations, the optimal medications for minimizing the likelihood of early readmissions were determined. This approach can help for identifying and managing most vulnerable patients thereby giving room to enhance post-discharge monitoring through clinical specialist supports to build critical-self management skills that will minimize the cost of diabetes care.
Identifiants
pubmed: 32561445
pii: S1532-0464(20)30114-3
doi: 10.1016/j.jbi.2020.103486
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
103486Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.