Integrative Systems Praxis for Implementation Research (INSPIRE): An Implementation Methodology to Facilitate the Global Elimination of Cervical Cancer.


Journal

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
ISSN: 1538-7755
Titre abrégé: Cancer Epidemiol Biomarkers Prev
Pays: United States
ID NLM: 9200608

Informations de publication

Date de publication:
09 2020
Historique:
received: 31 03 2020
revised: 09 06 2020
accepted: 11 06 2020
pubmed: 21 6 2020
medline: 22 12 2021
entrez: 21 6 2020
Statut: ppublish

Résumé

The World Health Organization (WHO) has called for a systems thinking approach to health systems strengthening to increase adoption of evidence-based interventions (EBI). The Integrative Systems Praxis for Implementation Research (INSPIRE) methodology operationalizes the WHO systems thinking framework to meet cervical cancer elimination-early detection and treatment (CC-EDT) goals. Using a systems thinking approach and grounded in the consolidated framework for implementation research, INSPIRE integrates multiple research methodologies and evaluation frameworks into a multilevel implementation strategy. In phase I (creating a shared understanding), soft systems methodology and pathway analysis are used to create a shared visual understanding of the CC-EDT system, incorporating diverse stakeholder perspectives of the "what, how, and why" of system behavior. Phase II (finding leverage) facilitates active stakeholder engagement in knowledge transfer and decision-making using deliberative dialogues and multiple scenario analyses. Phase III (acting strategically) represents stakeholder-engaged implementation planning, using well-defined implementation strategies of education, training, and infrastructure development. In phase IV (learning and adapting), evaluation of key performance indicators via a reach, effectiveness, adoption, implementation, and maintenance framework is reviewed by stakeholder teams, who continuously adapt implementation plans to improve system effectiveness. The INSPIRE methodology is a generalizable approach to context-adapted implementation of EBIs. Replacing static dissemination of implementation "roadmaps" with learning health systems through the integration of systems thinking and participatory action research, INSPIRE facilitates the development of scalable and sustainable implementation strategies adapted to local contexts.

Sections du résumé

BACKGROUND
The World Health Organization (WHO) has called for a systems thinking approach to health systems strengthening to increase adoption of evidence-based interventions (EBI). The Integrative Systems Praxis for Implementation Research (INSPIRE) methodology operationalizes the WHO systems thinking framework to meet cervical cancer elimination-early detection and treatment (CC-EDT) goals.
METHODS
Using a systems thinking approach and grounded in the consolidated framework for implementation research, INSPIRE integrates multiple research methodologies and evaluation frameworks into a multilevel implementation strategy.
RESULTS
In phase I (creating a shared understanding), soft systems methodology and pathway analysis are used to create a shared visual understanding of the CC-EDT system, incorporating diverse stakeholder perspectives of the "what, how, and why" of system behavior. Phase II (finding leverage) facilitates active stakeholder engagement in knowledge transfer and decision-making using deliberative dialogues and multiple scenario analyses. Phase III (acting strategically) represents stakeholder-engaged implementation planning, using well-defined implementation strategies of education, training, and infrastructure development. In phase IV (learning and adapting), evaluation of key performance indicators via a reach, effectiveness, adoption, implementation, and maintenance framework is reviewed by stakeholder teams, who continuously adapt implementation plans to improve system effectiveness.
CONCLUSIONS
The INSPIRE methodology is a generalizable approach to context-adapted implementation of EBIs.
IMPACT
Replacing static dissemination of implementation "roadmaps" with learning health systems through the integration of systems thinking and participatory action research, INSPIRE facilitates the development of scalable and sustainable implementation strategies adapted to local contexts.

Identifiants

pubmed: 32561563
pii: 1055-9965.EPI-20-0501
doi: 10.1158/1055-9965.EPI-20-0501
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1710-1719

Subventions

Organisme : NCI NIH HHS
ID : P30 CA118100
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA190366
Pays : United States

Informations de copyright

©2020 American Association for Cancer Research.

Auteurs

Patti E Gravitt (PE)

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland. pgravitt@som.umaryland.edu.

Anne F Rositch (AF)

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Magdalena Jurczuk (M)

Department of Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.

Graciela Meza (G)

Facultad de Medicina Humana, Universidad Nacional de la Amazonia Peruana, Iquitos, Peru.

Lita Carillo (L)

DIRESA-Loreto, Iquitos, Peru.

Jose Jeronimo (J)

Global Coalition Against Cervical Cancer, Arlington, Virginia.

Prajakta Adsul (P)

Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico.

Laura Nervi (L)

College of Population Health, University of New Mexico, Albuquerque, New Mexico.

Margaret Kosek (M)

Department of Medicine, University of Virginia, Charlottesville, Virginia.

J Kathleen Tracy (JK)

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH