Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report.


Journal

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
ISSN: 1878-3511
Titre abrégé: Int J Infect Dis
Pays: Canada
ID NLM: 9610933

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 24 02 2020
revised: 10 06 2020
accepted: 13 06 2020
pubmed: 21 6 2020
medline: 11 11 2020
entrez: 21 6 2020
Statut: ppublish

Résumé

Adenosine deaminase (ADA) in cerebrospinal fluid (CSF) is considered to be a useful biomarker in differentiating tuberculous meningitis (TBM) from other meningitis in non-HIV patients. However, its specificity decreases in patients with HIV, and other diseases such as cytomegalovirus encephalitis, toxoplasmosis or meningeal lymphomatosis can also elevate ADA in CSF. We here report a rare case of retroviral rebound syndrome in a HIV patient, whose ADA in CSF was elevated.

Identifiants

pubmed: 32562847
pii: S1201-9712(20)30485-9
doi: 10.1016/j.ijid.2020.06.050
pii:
doi:

Substances chimiques

Biomarkers 0
Adenosine Deaminase EC 3.5.4.4

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

297-298

Informations de copyright

Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Auteurs

Asako Doi (A)

Department of Infectious Diseases, Kobe City Medical Center General Hospital, Japan; Department of General Internal Medicine, Kobe City Medical Center General Hospital, Japan. Electronic address: asakodoi@gmail.com.

Toshikazu Hasuike (T)

Department of Infectious Diseases, Kobe City Medical Center General Hospital, Japan; Department of General Internal Medicine, Kobe City Medical Center General Hospital, Japan.

Tatsuya Shindo (T)

Department of General Internal Medicine, Kobe City Medical Center General Hospital, Japan.

Hiroaki Nishioka (H)

Department of Infectious Diseases, Kobe City Medical Center General Hospital, Japan; Department of General Internal Medicine, Kobe City Medical Center General Hospital, Japan.

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Classifications MeSH