Colorectal neuroendocrine tumors: A case series.

Case series Colorectal cancer Large bowel obstruction Neuroendocrine tumor Peritonitis

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
2020
Historique:
received: 07 05 2020
revised: 07 06 2020
accepted: 07 06 2020
pubmed: 22 6 2020
medline: 22 6 2020
entrez: 22 6 2020
Statut: ppublish

Résumé

Neuroendocrine tumors (NET) of the colon and sigmoid colon are uncommon compared to colorectal adenocarcinoma. Few reports have been made of NET of the colon and sigmoid colon that presents with peritonitis and large bowel obstruction. Here, we report two cases of NET of the colon and sigmoid colon, which were diagnosed and treated at our institution. In our first case, a 66-year-old man with a history of abdominal distension was diagnosed with NET via histopathology of the sigmoid colon. The second case involved a 45-year-old woman with the chief complaints of abdominal distention and inability to defecate; specimen histopathology of the descending colon showed neuroendocrine carcinoma features. Clinical outcome was very poor in our patients: eight months after the resection, the second patient demonstrated a sign of metastasis on the liver. An uncommon case of colon and sigmoid colon carcinoma with neuroendocrine and diagnostic difficulties precludes an exact description of the initial diagnostic criteria and management. Thus, our case series offers an overview of initial symptoms, radiological and histopathological features for early diagnosis, and proper management of NET.

Identifiants

pubmed: 32563832
pii: S2210-2612(20)30432-6
doi: 10.1016/j.ijscr.2020.06.030
pmc: PMC7306531
pii:
doi:

Types de publication

Journal Article

Langues

eng

Pagination

411-417

Informations de copyright

Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Références

Int J Surg. 2018 Dec;60:279-282
pubmed: 30359781
Histopathology. 2020 Jan;76(2):182-188
pubmed: 31433515
GE Port J Gastroenterol. 2015 Jul 02;22(5):213-220
pubmed: 28868410
Clinics (Sao Paulo). 2011;66(10):1671-5
pubmed: 22012036
JAMA Oncol. 2017 Oct 01;3(10):1335-1342
pubmed: 28448665
World J Clin Cases. 2019 Jul 26;7(14):1865-1875
pubmed: 31417933
Cancer. 1999 Sep 1;86(5):858-65
pubmed: 10463986
Cancer. 2017 Dec 15;123(24):4770-4790
pubmed: 29112233
J Clin Oncol. 2008 Jun 20;26(18):3063-72
pubmed: 18565894
J Visc Surg. 2014 Feb;151(1):3-7
pubmed: 24412088
Int J Endocr Oncol. 2016 Aug;3(3):203-219
pubmed: 30338051
Oman Med J. 2017 Sep;32(5):365-370
pubmed: 29026467
Am J Case Rep. 2019 Jun 28;20:920-925
pubmed: 31249283
J Natl Compr Canc Netw. 2018 Jun;16(6):693-702
pubmed: 29891520
Nat Rev Endocrinol. 2009 May;5(5):276-83
pubmed: 19444261
Ann Oncol. 2005 Aug;16(8):1374-80
pubmed: 15939719
J Gastrointest Oncol. 2018 Apr;9(2):354-357
pubmed: 29755775
Cir Cir. 2015 Sep-Oct;83(5):438-41
pubmed: 26319938
World J Gastroenterol. 2008 Sep 21;14(35):5377-84
pubmed: 18803349
PLoS One. 2017 Dec 12;12(12):e0188876
pubmed: 29232390
J Clin Oncol. 2007 May 20;25(15):1967-73
pubmed: 17513802
J Cancer. 2012;3:292-302
pubmed: 22773933
CA Cancer J Clin. 2017 Mar;67(2):93-99
pubmed: 28094848

Auteurs

Division of Digestive, Department of Surgery, Faculty of Medicine, Hasanuddin University Makassar, Indonesia. Electronic address: kbd.warsinggih@gmail.com.
Division of Digestive, Department of Surgery, Faculty of Medicine, Hasanuddin University Makassar, Indonesia. Electronic address: dr.liliyanto.lie@gmail.com.
Division of Oncology, Department of Surgery, Faculty of Medicine, Hasanuddin University Makassar, Indonesia. Electronic address: prihantono.md@gmail.com.

Gusti Deasy Wilda Ariani (GDW)

Department of Anatomic Pathology, Faculty of Medicine, Hasanuddin University Makassar, Indonesia. Electronic address: gusti.deasy@gmail.com.

Muhammad Faruk (M)

Department of Surgery, Faculty of Medicine, Hasanuddin University Makassar, Indonesia. Electronic address: faroex8283@gmail.com.

Classifications MeSH