Influence of gut microbiota on mucosal IgA antibody response to the polio vaccine.
Health care
Immunology
Microbiology
Journal
NPJ vaccines
ISSN: 2059-0105
Titre abrégé: NPJ Vaccines
Pays: England
ID NLM: 101699863
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
09
2019
accepted:
12
05
2020
entrez:
23
6
2020
pubmed:
23
6
2020
medline:
23
6
2020
Statut:
epublish
Résumé
The impact of intestinal microbiota on mucosal antibody response to the polio vaccine is poorly understood. We examined changes in vaccine-induced intestinal mucosal immunity to poliovirus by measuring the immunoglobulin A (IgA) antibody levels in stool samples collected from 107 infants in China, and the samples were collected 14 days after different sequential vaccinations combining inactivated polio vaccine (IPV) with oral poliovirus vaccine (OPV). Gut microbiota were identified using 16S ribosomal RNA sequencing 28 days before, 14 days before, and at the last dose of OPV. Vaccine-induced type 2-specific mucosal IgA showed a decrease after switching from trivalent to bivalent OPV (bOPV) (positive rate of polio type 2-specific mucosal IgA, 16.7%, 11.8%, and 45.9% for IPV + 2bOPV, 2IPV + bOPV, and 2IPV + trivalent OPV groups, respectively). The composition of the gut microbiome was significantly different, a higher abundance of
Identifiants
pubmed: 32566258
doi: 10.1038/s41541-020-0194-5
pii: 194
pmc: PMC7283253
doi:
Types de publication
Journal Article
Langues
eng
Pagination
47Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing interests.
Références
Cell. 2015 Oct 8;163(2):367-80
pubmed: 26411289
Vaccine. 2014 Mar 10;32(12):1382-7
pubmed: 24492016
Nat Methods. 2013 Oct;10(10):996-8
pubmed: 23955772
Bioinformatics. 2011 Nov 1;27(21):2957-63
pubmed: 21903629
Expert Rev Vaccines. 2015 May;14(5):749-62
pubmed: 25597843
Pediatr Res. 1993 May;33(5):475-80
pubmed: 8390047
Nat Methods. 2013 Jan;10(1):57-9
pubmed: 23202435
Bioinformatics. 2011 Aug 15;27(16):2194-200
pubmed: 21700674
J Infect Dis. 2000 Jul;182(1):1-5
pubmed: 10882574
J Infect Dis. 2010 Sep 1;202 Suppl:S87-92
pubmed: 20684723
Lancet Infect Dis. 2016 Aug;16(8):905-14
pubmed: 27156189
Pediatrics. 2014 Aug;134(2):e362-72
pubmed: 25002669
Vaccine. 2003 Jul 28;21(24):3374-6
pubmed: 12850343
Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19;370(1671):
pubmed: 25964463
Lancet. 2016 Jul 9;388(10040):158-69
pubmed: 27212429
Hum Vaccin. 2010 Jul;6(7):532-42
pubmed: 20622508
FEMS Microbiol Rev. 2011 Mar;35(2):343-59
pubmed: 21039646
Lancet Infect Dis. 2010 May;10(5):338-49
pubmed: 20417416
Trends Immunol. 2013 Sep;34(9):431-9
pubmed: 23680130
ISME J. 2012 Aug;6(8):1621-4
pubmed: 22402401
Hum Hered. 2011;72(2):121-32
pubmed: 21996641
Science. 2011 Oct 14;334(6053):249-52
pubmed: 21998395
J Infect Dis. 2018 Jan 17;217(3):371-380
pubmed: 29304199
Pediatr Infect Dis J. 1993 Aug;12(8):664-71
pubmed: 8414780
Genome Res. 2011 Mar;21(3):494-504
pubmed: 21212162
Ann Nutr Metab. 2016;69 Suppl 2:42-51
pubmed: 28103609
PLoS One. 2012;7(8):e41720
pubmed: 22879893
Lancet Infect Dis. 2016 Dec;16(12):1377-1384
pubmed: 27638357
Lancet Infect Dis. 2016 Aug;16(8):868-9
pubmed: 27156190
J Infect Dis. 2012 May 15;205(10):1554-61
pubmed: 22448007
Vaccine. 2013 Jan 7;31(3):452-60
pubmed: 23153448
Nature. 2013 Aug 8;500(7461):232-6
pubmed: 23842501
Vaccine. 2017 Sep 18;35(39):5235-5241
pubmed: 28822643
Gut Microbes. 2018 Mar 4;9(2):93-101
pubmed: 28891751
Nature. 2018 Oct;562(7728):583-588
pubmed: 30356187
Trends Mol Med. 2012 Jun;18(6):328-36
pubmed: 22633998
Annu Rev Nutr. 2014;34:143-69
pubmed: 24850388
Vaccine. 2018 Jan 4;36(2):264-272
pubmed: 29217369
Pediatrics. 2016 Dec;138(6):
pubmed: 27940670
Trends Immunol. 2014 Mar;35(3):97-104
pubmed: 24239225
J Infect Dis. 2009 Sep 1;200(5):794-801
pubmed: 19624278
PLoS Pathog. 2012;8(4):e1002599
pubmed: 22532797
PLoS One. 2013 Apr 24;8(4):e62026
pubmed: 23637957
BMC Biol. 2010 Oct 04;8:129
pubmed: 20920375
Genome Biol. 2011 Jun 24;12(6):R60
pubmed: 21702898
FEMS Immunol Med Microbiol. 2008 Jun;53(1):107-13
pubmed: 18422632
J Infect Dis. 1991 Jan;163(1):1-6
pubmed: 1845806
J Infect Dis. 2019 Apr 8;219(8):1178-1186
pubmed: 30247561
J Infect Dis. 1995 May;171(5):1097-106
pubmed: 7751683
Lancet Infect Dis. 2019 Apr;19(4):359-360
pubmed: 30938297
Vaccine. 2002 Nov 22;21(1-2):138-45
pubmed: 12443672
Risk Anal. 2013 Apr;33(4):606-46
pubmed: 23550968
Dev Psychobiol. 2019 Jul;61(5):714-728
pubmed: 30663777
Nat Methods. 2010 May;7(5):335-6
pubmed: 20383131
Vaccine. 2018 Jun 7;36(24):3427-3433
pubmed: 29752022
Lancet Infect Dis. 2017 Oct;17(10):1069-1079
pubmed: 28693854