Somatic genetic aberrations in benign breast disease and the risk of subsequent breast cancer.
Breast cancer
Cancer genomics
Cancer prevention
Journal
NPJ breast cancer
ISSN: 2374-4677
Titre abrégé: NPJ Breast Cancer
Pays: United States
ID NLM: 101674891
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
09
2019
accepted:
08
05
2020
entrez:
23
6
2020
pubmed:
23
6
2020
medline:
23
6
2020
Statut:
epublish
Résumé
It is largely unknown how the development of breast cancer (BC) is transduced by somatic genetic alterations in the benign breast. Since benign breast disease is an established risk factor for BC, we established a case-control study of women with a history of benign breast biopsy (BBB). Cases developed BC at least one year after BBB and controls did not develop BC over an average of 17 years following BBB. 135 cases were matched to 69 controls by age and type of benign change: non-proliferative or proliferation without atypia (PDWA). Whole-exome sequencing (WES) was performed for the BBB. Germline DNA (available from
Identifiants
pubmed: 32566745
doi: 10.1038/s41523-020-0165-z
pii: 165
pmc: PMC7293275
doi:
Types de publication
Journal Article
Langues
eng
Pagination
24Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare no competing interests.
Références
Cancer Discov. 2019 Feb;9(2):176-198
pubmed: 30679171
Cancer Cell. 2018 Dec 10;34(6):893-905.e8
pubmed: 30537512
Nature. 2016 May 02;534(7605):47-54
pubmed: 27135926
CA Cancer J Clin. 2019 Jan;69(1):7-34
pubmed: 30620402
Genome Med. 2017 Jun 29;9(1):59
pubmed: 28659176
Nature. 2014 Aug 14;512(7513):155-60
pubmed: 25079324
Ann Surg Oncol. 2019 Jul;26(7):2127-2135
pubmed: 30815800
Genome Res. 2012 Mar;22(3):568-76
pubmed: 22300766
J Mol Diagn. 2013 Sep;15(5):623-33
pubmed: 23810758
Nature. 2012 Apr 18;486(7403):346-52
pubmed: 22522925
J Natl Cancer Inst. 2007 Nov 21;99(22):1695-705
pubmed: 18000216
Nat Genet. 2013 Sep;45(9):970-6
pubmed: 23852170
Nat Rev Mol Cell Biol. 2008 Aug;9(8):616-27
pubmed: 18594563
J Clin Oncol. 2015 Mar 10;33(8):923-9
pubmed: 25624442
J Natl Cancer Inst. 1989 Dec 20;81(24):1879-86
pubmed: 2593165
Genome Biol. 2011;12(4):R41
pubmed: 21527027
Curr Biol. 2002 Jun 4;12(11):912-8
pubmed: 12062055
Cell. 2002 Dec 13;111(6):779-89
pubmed: 12526805
Cell. 2018 Apr 5;173(2):371-385.e18
pubmed: 29625053
Sci Rep. 2013 Oct 02;3:2650
pubmed: 24084849
Nat Cell Biol. 2016 Nov;18(11):1185-1195
pubmed: 27723720
Nat Biotechnol. 2013 Mar;31(3):213-9
pubmed: 23396013
J Am Coll Surg. 2009 Oct;209(4):504-20
pubmed: 19801324
Br J Cancer. 2018 Jun;118(12):1662-1664
pubmed: 29872146
Bioinformatics. 2010 Mar 1;26(5):589-95
pubmed: 20080505
J Clin Oncol. 2010 Aug 1;28(22):3591-6
pubmed: 20606088
Nat Commun. 2019 Dec 11;10(1):5666
pubmed: 31827079
DNA Repair (Amst). 2018 Feb;62:1-7
pubmed: 29223032
Genome Biol. 2016 Jun 06;17(1):122
pubmed: 27268795
Genome Res. 2010 Sep;20(9):1297-303
pubmed: 20644199
Cancer Res. 2017 Sep 15;77(18):4755-4762
pubmed: 28904067
Science. 2015 May 22;348(6237):880-6
pubmed: 25999502
PLoS Genet. 2008 Jun 13;4(6):e1000092
pubmed: 18551179
Cell Stem Cell. 2010 Sep 3;7(3):403-17
pubmed: 20804975
Cancer. 2016 Feb 1;122(3):378-85
pubmed: 26512815
Nat Genet. 2015 Dec;47(12):1402-7
pubmed: 26551669
Nucleic Acids Res. 2008 Apr;36(7):2174-81
pubmed: 18276636
Nat Genet. 2013 Mar;45(3):253-61
pubmed: 23354438
Genet Test Mol Biomarkers. 2010 Aug;14(4):533-7
pubmed: 20642364
Genet Med. 2018 Oct;20(10):1196-1205
pubmed: 29388947
Nat Med. 2009 Aug;15(8):907-13
pubmed: 19648928
Nat Rev Cancer. 2001 Nov;1(2):157-62
pubmed: 11905807
Mol Oncol. 2016 Feb;10(2):360-70
pubmed: 26643573
Nucleic Acids Res. 2010 Sep;38(16):e164
pubmed: 20601685
Nat Commun. 2018 Jul 9;9(1):2372
pubmed: 29985391
BMC Genomics. 2019 Sep 2;20(1):689
pubmed: 31477010
Cancer. 1993 Feb 15;71(4):1258-65
pubmed: 8435803
Breast Cancer Res Treat. 2015 Jun;151(3):709-15
pubmed: 25981900
Nat Genet. 2013 Oct;45(10):1127-33
pubmed: 24071851
Cell. 2019 Mar 7;176(6):1282-1294.e20
pubmed: 30849372
Nature. 2017 Mar 30;543(7647):714-718
pubmed: 28329761
Nature. 2009 Apr 9;458(7239):719-24
pubmed: 19360079
J Clin Oncol. 2008 Nov 20;26(33):5374-9
pubmed: 18854574
N Engl J Med. 2005 Jul 21;353(3):229-37
pubmed: 16034008
Front Med (Lausanne). 2019 Jul 24;6:166
pubmed: 31396514
Fly (Austin). 2012 Apr-Jun;6(2):80-92
pubmed: 22728672
Proc Natl Acad Sci U S A. 2014 May 27;111(21):7789-94
pubmed: 24821780
EMBO J. 2004 Aug 4;23(15):3164-74
pubmed: 15282542
Nature. 2015 Jan 29;517(7536):635-9
pubmed: 25409153
N Engl J Med. 1985 Jan 17;312(3):146-51
pubmed: 3965932
Biol Chem. 2001 Feb;382(2):143-9
pubmed: 11308013
Cancer Prev Res (Phila). 2017 Jan;10(1):89-97
pubmed: 27789587
Nucleic Acids Res. 1994 Dec 25;22(25):5658-64
pubmed: 7838719
Nat Commun. 2019 Jun 12;10(1):2569
pubmed: 31189880
JAMA Oncol. 2017 Apr 1;3(4):464-471
pubmed: 27978560
Nature. 2006 Nov 30;444(7119):633-7
pubmed: 17136093
Nature. 2013 Aug 22;500(7463):415-21
pubmed: 23945592
Nat Commun. 2018 May 10;9(1):1857
pubmed: 29748584
Breast Cancer (Auckl). 2016 Aug 17;10:109-46
pubmed: 27559297
Nucleic Acids Res. 2016 Jun 20;44(11):e108
pubmed: 27060149