Analysis of Characteristics and Survival of Primary Cutaneous Adenoid Cystic Carcinoma of the Head and Neck.
Age Factors
Aged
Carcinoma, Adenoid Cystic
/ mortality
Comorbidity
Databases, Factual
Female
Head and Neck Neoplasms
/ mortality
Humans
Insurance Coverage
Insurance, Health
Kaplan-Meier Estimate
Male
Middle Aged
Proportional Hazards Models
Sex Factors
Skin Neoplasms
/ mortality
United States
/ epidemiology
NCDB
National Cancer Database
cancer
primary cutaneous adenoid cystic carcinoma
survival
Journal
The Annals of otology, rhinology, and laryngology
ISSN: 1943-572X
Titre abrégé: Ann Otol Rhinol Laryngol
Pays: United States
ID NLM: 0407300
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
pubmed:
23
6
2020
medline:
5
1
2021
entrez:
23
6
2020
Statut:
ppublish
Résumé
Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare skin tumor. The head and neck (H&N) is the most common anatomical location. Due to limited published cases, its clinical course and management are not well understood. The National Cancer Database (NCDB) was queried for all cases of H&N PCACC diagnosed from 2004 to 2016. Kaplan-Meier (KM) and Cox proportional hazards models were used to determine clinicopathological and treatment factors associated with survival outcomes. A total of 201 cases were analyzed. The average age of diagnosis was 57.7 years (± SD 15.8). There was a female predilection (57.7%; This study represents the largest cohort of H&N PCACC studied to date and provides important clinicopathologic information for this rare tumor. Additionally, our results emphasize the importance of health insurance as an independent predictor of survival in PCACC.
Sections du résumé
BACKGROUND/OBJECTIVES
OBJECTIVE
Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare skin tumor. The head and neck (H&N) is the most common anatomical location. Due to limited published cases, its clinical course and management are not well understood.
METHODS
METHODS
The National Cancer Database (NCDB) was queried for all cases of H&N PCACC diagnosed from 2004 to 2016. Kaplan-Meier (KM) and Cox proportional hazards models were used to determine clinicopathological and treatment factors associated with survival outcomes.
RESULTS
RESULTS
A total of 201 cases were analyzed. The average age of diagnosis was 57.7 years (± SD 15.8). There was a female predilection (57.7%;
CONCLUSION
CONCLUSIONS
This study represents the largest cohort of H&N PCACC studied to date and provides important clinicopathologic information for this rare tumor. Additionally, our results emphasize the importance of health insurance as an independent predictor of survival in PCACC.
Identifiants
pubmed: 32567392
doi: 10.1177/0003489420936719
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM