nCOV-19 peptides mass fingerprinting identification, binding, and blocking of inhibitors flavonoids and anthraquinone of
AutoDock Vina
COVID-19
SARS-CoV-2
anthraquinone
flavonoids
hydroxychloroquine
peptide mass fingerprinting
Journal
Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
pubmed:
23
6
2020
medline:
1
7
2021
entrez:
23
6
2020
Statut:
ppublish
Résumé
An rare pandemic of viral pneumonia occurs in December 2019 in Wuhan, China, which is now recognized internationally as Corona Virus Disease 2019 (COVID-19), the etiological agent classified as Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2). According to the World Health Organization (WHO), it has so far expanded to more than 213 countries/territories worldwide. Our study aims to find the viral peptides of SARS-COV-2 by peptide mass fingerprinting (PMF) in order to predict its novel structure and find an inhibitor for each viral peptide. For this reason, we calculated the mass of amino acid sequences translated from the SARS-CoV2 whole genome and identify the peptides that may be a target for inhibition. Molecular peptide docking with
Identifiants
pubmed: 32567487
doi: 10.1080/07391102.2020.1778534
pmc: PMC7332867
doi:
Substances chimiques
Anthraquinones
0
Flavonoids
0
Peptides
0
RNA, Viral
0
Hydroxychloroquine
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Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM