Remdesivir (GS-5734) as a therapeutic option of 2019-nCOV main protease -
2019-nCOV
COVID-19
Remdesivir
dynamics simulations
molecular docking
phylogeny
sequence analysis
Journal
Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
pubmed:
23
6
2020
medline:
4
8
2021
entrez:
23
6
2020
Statut:
ppublish
Résumé
2019 - Novel Coronavirus (2019-nCOV), enclosed large genome positive-sense RNA virus characterized by crown-like spikes that protrude from their surface, and have a distinctive replication strategy. The 2019-nCOV belongs to the Coronaviridae family, principally consists of virulent pathogens showing zoonotic property, has emerged as a pandemic outbreak with high mortality and high morbidity rate around the globe and no therapeutic vaccine or drugs against 2019-nCoV are discovered till now. In this study,
Identifiants
pubmed: 32568620
doi: 10.1080/07391102.2020.1781694
pmc: PMC7332877
doi:
Substances chimiques
Protease Inhibitors
0
remdesivir
3QKI37EEHE
Adenosine Monophosphate
415SHH325A
Peptide Hydrolases
EC 3.4.-
Alanine
OF5P57N2ZX
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4701-4714Références
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