Toxicological, chemopreventive, and cytotoxic potentialities of rare vegetal species and supporting findings for the Brazilian Unified Health System (SUS).
Antineoplastic Agents, Phytogenic
/ chemistry
Antioxidants
/ chemistry
Brazil
Cell Cycle
/ drug effects
Cells, Cultured
Cytotoxins
/ chemistry
DNA Damage
Ecosystem
Ecotoxicology
Humans
Methylene Chloride
/ chemistry
Oxidative Stress
/ drug effects
Plant Extracts
/ chemistry
Plants, Medicinal
/ chemistry
Oxidative stress
antitumoral action
cell cycle arrest
environmental toxicology
genotoxicity
Journal
Journal of toxicology and environmental health. Part A
ISSN: 1528-7394
Titre abrégé: J Toxicol Environ Health A
Pays: England
ID NLM: 100960995
Informations de publication
Date de publication:
17 07 2020
17 07 2020
Historique:
pubmed:
23
6
2020
medline:
26
2
2021
entrez:
23
6
2020
Statut:
ppublish
Résumé
Caatinga flora which are found in a poor Brazilian region contain a substantial number of endemic taxa with biomedical and social importance for regional communities. This study examined the antioxidant and cytotoxic potential of 35 samples (extracts/fractions) from 12 Caatinga species and determined the antiproliferative and genotoxic action of dichloromethane fraction from ABTS: 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid); AcOH: ethyl acetate; ANOVA: analysis of variance; SUS: Brazilian Unified Health System; DC-Mca: dichloromethane fraction from
Identifiants
pubmed: 32568625
doi: 10.1080/15287394.2020.1780658
doi:
Substances chimiques
Antineoplastic Agents, Phytogenic
0
Antioxidants
0
Cytotoxins
0
Plant Extracts
0
Methylene Chloride
588X2YUY0A
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM