Ouabain and Marinobufagenin: Physiological Effects on Human Epithelial and Endothelial Cells.
Journal
Biochemistry. Biokhimiia
ISSN: 1608-3040
Titre abrégé: Biochemistry (Mosc)
Pays: United States
ID NLM: 0376536
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
entrez:
23
6
2020
pubmed:
23
6
2020
medline:
14
1
2021
Statut:
ppublish
Résumé
Long-term study on the identification of Na,K-ATPase endogenous inhibitors in mammalian tissues has resulted in the discovery of ouabain, marinobufagenin (MBG), and other cardiotonic steroids (CTS) in the blood plasma. Production of ouabain and MBG is increased in essential hypertension and other diseases associated with hypervolemia. Here, we compared the effects of ouabain and MBG on the Na,K-ATPase activity (measured as the transport of Na+, K+, and Rb
Identifiants
pubmed: 32569558
pii: BCM85040587
doi: 10.1134/S0006297920040112
doi:
Substances chimiques
Bufanolides
0
Cardiotonic Agents
0
Vasoconstrictor Agents
0
marinobufagenin
3KBT25GV2B
Ouabain
5ACL011P69
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM