Protocol for a randomised controlled trial to investigate the effect of home- and gym-based resistance exercise training on glycaemic control, body composition and muscle strength.
Adult
Aged
Aged, 80 and over
Body Composition
Diabetes Mellitus, Type 2
/ blood
Female
Follow-Up Studies
Glycated Hemoglobin
/ analysis
Glycemic Control
/ methods
Humans
Kuwait
/ epidemiology
Male
Middle Aged
Muscle Strength
Quality of Life
Randomized Controlled Trials as Topic
Resistance Training
/ methods
Treatment Outcome
Young Adult
Diabetes
Glycaemic control
Home-based
Resistance exercise
Unsupervised
Journal
Trials
ISSN: 1745-6215
Titre abrégé: Trials
Pays: England
ID NLM: 101263253
Informations de publication
Date de publication:
22 Jun 2020
22 Jun 2020
Historique:
received:
07
11
2019
accepted:
06
06
2020
entrez:
24
6
2020
pubmed:
24
6
2020
medline:
18
3
2021
Statut:
epublish
Résumé
Resistance exercise is known to be effective in reducing glycated haemoglobin (HbA1c) in people with type 2 diabetes. However, studies, so far, have employed supervised resistance exercise in a laboratory or gym facility which limits the future translation of such exercise in to clinical practice and recommendations. Our primary aim, therefore, is to test the hypothesis, in a randomized controlled trial, that home-based resistance exercise training and gym-based resistance exercise training both reduce HbA1c levels in people with type 2 diabetes compared to control. We will also investigate the effects of home- and gym-based resistance exercise training on muscle strength and body composition. The current study is a three-arm randomised controlled trial which will be conducted with 150 eligible people with type 2 diabetes to compare home-and gym-based resistance exercise training with usual care in Kuwait. The interventions will be delivered by exercise specialists and last for 32 weeks. The primary outcomes are HbA1c with secondary outcomes measuring muscle function, body composition, physical activity and quality of life. Ethical approval has been granted by the Dasman Diabetes Institute ethical review committee (RA/197/2019). Study findings will be disseminated through presentation at scientific conferences and in scientific journals. NCT04136730: Retrospectively registered on 21 October 2019.
Sections du résumé
BACKGROUND
BACKGROUND
Resistance exercise is known to be effective in reducing glycated haemoglobin (HbA1c) in people with type 2 diabetes. However, studies, so far, have employed supervised resistance exercise in a laboratory or gym facility which limits the future translation of such exercise in to clinical practice and recommendations. Our primary aim, therefore, is to test the hypothesis, in a randomized controlled trial, that home-based resistance exercise training and gym-based resistance exercise training both reduce HbA1c levels in people with type 2 diabetes compared to control. We will also investigate the effects of home- and gym-based resistance exercise training on muscle strength and body composition.
METHODS
METHODS
The current study is a three-arm randomised controlled trial which will be conducted with 150 eligible people with type 2 diabetes to compare home-and gym-based resistance exercise training with usual care in Kuwait. The interventions will be delivered by exercise specialists and last for 32 weeks. The primary outcomes are HbA1c with secondary outcomes measuring muscle function, body composition, physical activity and quality of life.
DISCUSSION
CONCLUSIONS
Ethical approval has been granted by the Dasman Diabetes Institute ethical review committee (RA/197/2019). Study findings will be disseminated through presentation at scientific conferences and in scientific journals.
TRIAL REGISTRATION
BACKGROUND
NCT04136730: Retrospectively registered on 21 October 2019.
Identifiants
pubmed: 32571396
doi: 10.1186/s13063-020-04480-2
pii: 10.1186/s13063-020-04480-2
pmc: PMC7310149
doi:
Substances chimiques
Glycated Hemoglobin A
0
hemoglobin A1c protein, human
0
Banques de données
ClinicalTrials.gov
['NCT04136730']
Types de publication
Clinical Trial Protocol
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
557Subventions
Organisme : Montreal Medical International, Kuwait
ID : NA
Commentaires et corrections
Type : ErratumIn
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