Drum training induces long-term plasticity in the cerebellum and connected cortical thickness.
Adolescent
Brain
/ physiology
Brain Mapping
/ methods
Cerebellar Cortex
/ physiology
Cerebellum
/ physiology
Female
Humans
Image Processing, Computer-Assisted
/ methods
Magnetic Resonance Imaging
/ methods
Male
Motor Activity
/ physiology
Music Therapy
/ methods
Neuronal Plasticity
/ physiology
Parietal Lobe
/ physiology
White Matter
/ physiology
Young Adult
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
22 06 2020
22 06 2020
Historique:
received:
28
11
2019
accepted:
06
04
2020
entrez:
24
6
2020
pubmed:
24
6
2020
medline:
12
1
2021
Statut:
epublish
Résumé
It is unclear to what extent cerebellar networks show long-term plasticity and accompanied changes in cortical structures. Using drumming as a demanding multimodal motor training, we compared cerebellar lobular volume and white matter microstructure, as well as cortical thickness of 15 healthy non-musicians before and after learning to drum, and 16 age matched novice control participants. After 8 weeks of group drumming instruction, 3 ×30 minutes per week, we observed the cerebellum significantly changing its grey (volume increase of left VIIIa, relative decrease of VIIIb and vermis Crus I volume) and white matter microstructure in the inferior cerebellar peduncle. These plastic cerebellar changes were complemented by changes in cortical thickness (increase in left paracentral, right precuneus and right but not left superior frontal thickness), suggesting an interplay of cerebellar learning with cortical structures enabled through cerebellar pathways.
Identifiants
pubmed: 32572037
doi: 10.1038/s41598-020-65877-2
pii: 10.1038/s41598-020-65877-2
pmc: PMC7308330
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
10116Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
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