Genome-wide associations of human gut microbiome variation and implications for causal inference analyses.

Animals Bifidobacterium / genetics Feces / microbiology Gastrointestinal Microbiome / genetics Genome-Wide Association Study Genotype Humans Mice Microbiota / genetics Phenotype Polymorphism, Single Nucleotide Quantitative Trait Loci RNA, Ribosomal, 16S / genetics

Journal

Nature microbiology
ISSN: 2058-5276
Titre abrégé: Nat Microbiol
Pays: England
ID NLM: 101674869

Informations de publication

Date de publication:
09 2020
Historique:
received: 07 08 2019
accepted: 18 05 2020
pubmed: 24 6 2020
medline: 18 11 2020
entrez: 24 6 2020
Statut: ppublish

Résumé

Recent population-based

Identifiants

DOI: 10.1038/s41564-020-0743-8 PMID: 32572223 PMC: PMC7610462
pubmed: 32572223
doi: 10.1038/s41564-020-0743-8
pii: 10.1038/s41564-020-0743-8
pmc: PMC7610462
mid: EMS118385
doi:

Substances chimiques

RNA, Ribosomal, 16S 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1079-1087

Subventions

Organisme : Medical Research Council
ID : MC_UU_00011/6
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12013/3
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 202802
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 202802/Z/16/Z
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C18281/A19169
Pays : United Kingdom
Organisme : Department of Health
ID : BRC-1215-20011
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 204813/Z/16/Z
Pays : United Kingdom

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Auteurs

David A Hughes (DA)

MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
ORCID: 0000-0002-9644-8998

Rodrigo Bacigalupe (R)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Jun Wang (J)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.
Institute of Microbiology, Chinese Academy of Sciences, Chaoyang District, Beijing, China.

Malte C Rühlemann (MC)

Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
ORCID: 0000-0002-0685-0052

Raul Y Tito (RY)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Gwen Falony (G)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.
ORCID: 0000-0003-2450-0782

Marie Joossens (M)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.
ORCID: 0000-0001-8410-5528

Sara Vieira-Silva (S)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.
ORCID: 0000-0002-4616-7602

Liesbet Henckaerts (L)

Department of Microbiology, Immunology and Transplantation, KU Leuven-University of Leuven, Leuven, Belgium.
Department of General Internal Medicine, KU Leuven-University Hospitals Leuven, Leuven, Belgium.
ORCID: 0000-0003-2880-1400

Leen Rymenans (L)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Chloë Verspecht (C)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium.
Center for Microbiology, VIB, Leuven, Belgium.

Susan Ring (S)

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Bristol Bioresource Laboratories, University of Bristol, Bristol, UK.

Andre Franke (A)

Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany.
ORCID: 0000-0003-1530-5811

Kaitlin H Wade (KH)

MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Nicholas J Timpson (NJ)

MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK. N.J.Timpson@bristol.ac.uk.
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. N.J.Timpson@bristol.ac.uk.
ORCID: 0000-0002-7141-9189

Jeroen Raes (J)

Department of Microbiology and Immunology, Rega Instituut, KU Leuven-University of Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be.
Center for Microbiology, VIB, Leuven, Belgium. jeroen.raes@kuleuven.be.
ORCID: 0000-0002-1337-041X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Genome-wide associations of human gut...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes irréguliers à Gram positif › Actinobacteria › Bifidobacterium › Genome-wide associations of human gut...
questionsmedicales.fr › Liquides et sécrétions biologiques › Fèces › Genome-wide associations of human gut...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Genome-wide associations of human gut...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Genome-wide associations of human gut...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Genome-wide associations of human gut...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genome-wide associations of human gut...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Genome-wide associations of human gut...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Genome-wide associations of human gut...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Genome-wide associations of human gut...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › Polymorphisme de nucléotide simple › Genome-wide associations of human gut...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Locus génétiques › Locus de caractère quantitatif › Genome-wide associations of human gut...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN ribosomique › ARN ribosomique 16S › Genome-wide associations of human gut...