The Interplay between Adeno-Associated Virus and its Helper Viruses.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
19 06 2020
Historique:
received: 30 05 2020
revised: 15 06 2020
accepted: 18 06 2020
entrez: 25 6 2020
pubmed: 25 6 2020
medline: 17 2 2021
Statut: epublish

Résumé

The adeno-associated virus (AAV) is a small, nonpathogenic parvovirus, which depends on helper factors to replicate. Those helper factors can be provided by coinfecting helper viruses such as adenoviruses, herpesviruses, or papillomaviruses. We review the basic biology of AAV and its most-studied helper viruses, adenovirus type 5 (AdV5) and herpes simplex virus type 1 (HSV-1). We further outline the direct and indirect interactions of AAV with those and additional helper viruses.

Identifiants

pubmed: 32575422
pii: v12060662
doi: 10.3390/v12060662
pmc: PMC7354565
pii:
doi:

Substances chimiques

Viral Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Anita F Meier (AF)

Institute of Virology, University of Zurich, CH-8057 Zurich, Switzerland.

Cornel Fraefel (C)

Institute of Virology, University of Zurich, CH-8057 Zurich, Switzerland.

Michael Seyffert (M)

Institute of Virology, University of Zurich, CH-8057 Zurich, Switzerland.

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