Update on Circulating Tumor Cells in Genitourinary Tumors with Focus on Prostate Cancer.
circulating tumor cells
genitourinary cancers
immune checkpoint inhibitors
liquid biopsy
precision oncology
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
19 06 2020
19 06 2020
Historique:
received:
25
05
2020
revised:
12
06
2020
accepted:
17
06
2020
entrez:
25
6
2020
pubmed:
25
6
2020
medline:
10
4
2021
Statut:
epublish
Résumé
Current developments in the treatment of genitourinary tumors underline the unmet clinical need for biomarkers to improve decision-making in a challenging clinical setting. The detection of circulating tumor cells (CTCs) has become one of the most exciting and important new approaches to identifying biomarkers at different stages of disease in a non-invasive way. Potential applications of CTCs include monitoring treatment efficacy and early detection of progression, selecting tailored therapies, as well as saving treatment costs. However, despite the promising implementation of CTCs in a clinical scenario, the isolation and characterization of these cells for molecular studies remain expensive with contemporary platforms, and significant technical challenges still need to be overcome. This updated, critical review focuses on the state of CTCs in patients with genitourinary tumor with focus on prostate cancer, discussing technical issues, main clinical results and hypothesizing potential future perspectives in clinical scenarios.
Identifiants
pubmed: 32575429
pii: cells9061495
doi: 10.3390/cells9061495
pmc: PMC7348874
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
BJU Int. 2019 May;123(5):769-776
pubmed: 30281887
Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2357-E2364
pubmed: 28270604
Cell. 2015 May 21;161(5):1215-1228
pubmed: 26000489
Mol Cell Biol. 2016 Jun 15;36(13):1836-55
pubmed: 27141054
Nat Methods. 2015 Jul;12(7):685-91
pubmed: 25984697
JAMA Oncol. 2019 Apr 01;5(4):471-478
pubmed: 30589920
Clin Cancer Res. 2008 Oct 1;14(19):6302-9
pubmed: 18829513
BMC Cancer. 2015 May 06;15:360
pubmed: 25944336
Biotechnol Adv. 2018 Jul - Aug;36(4):1063-1078
pubmed: 29559380
Ther Adv Med Oncol. 2019 Nov 25;11:1758835919890285
pubmed: 31803255
Anal Chem. 2017 Aug 1;89(15):7924-7932
pubmed: 28661138
Eur Urol. 2019 Jul;76(1):89-97
pubmed: 30553611
Science. 2018 Feb 16;359(6377):801-806
pubmed: 29301960
Future Oncol. 2019 Jul;15(19):2199-2202
pubmed: 31213082
Discov Med. 2014 Feb;17(92):101-14
pubmed: 24534473
N Engl J Med. 2015 Feb 26;372(9):793-5
pubmed: 25635347
Clin Cancer Res. 2005 Apr 1;11(7):2625-36
pubmed: 15814643
Eur Urol. 2016 Sep;70(3):516-21
pubmed: 26149668
Cancer Epidemiol Biomarkers Prev. 2009 Aug;18(8):2190-4
pubmed: 19661076
Clin Cancer Res. 2013 Jun 15;19(12):3259-67
pubmed: 23620406
Eur Urol. 2017 Mar;71(3):405-414
pubmed: 27751729
J Clin Oncol. 2015 Mar 1;33(7):723-31
pubmed: 25624429
Tumori. 2018 Oct;104(5):401-405
pubmed: 29192741
Clin Cancer Res. 2004 Oct 15;10(20):6897-904
pubmed: 15501967
Cancer Cell. 2008 Dec 9;14(6):435-46
pubmed: 19061835
Prostate. 2018 Jun;78(8):576-582
pubmed: 29508425
Int J Urol. 2010 Mar;17(3):254-8
pubmed: 20148989
Expert Rev Mol Diagn. 2020 Feb;20(2):135-139
pubmed: 31509027
Nat Rev Dis Primers. 2017 Mar 09;3:17009
pubmed: 28276433
Clin Cancer Res. 2019 Jan 1;25(1):43-51
pubmed: 30232224
Eur Urol Oncol. 2020 Aug;3(4):498-508
pubmed: 31412010
Eur Urol. 2018 May;73(5):653-655
pubmed: 29458983
JCO Precis Oncol. 2018;2018:
pubmed: 30761387
J Clin Oncol. 2019 May 1;37(13):1120-1129
pubmed: 30865549
Urology. 2011 Oct;78(4):863-7
pubmed: 21813167
J Clin Oncol. 2018 Feb 20;36(6):572-580
pubmed: 29272162
Eur Urol. 2020 Apr;77(4):420-433
pubmed: 31563503
Nat Rev Genet. 2019 Feb;20(2):71-88
pubmed: 30410101
Chem Rev. 2007 May;107(5):1387-407
pubmed: 17455916
N Engl J Med. 2019 Jul 25;381(4):338-348
pubmed: 31340094
Lab Chip. 2010 Jan 7;10(1):27-9
pubmed: 20024046
Cancer Cell. 2014 Sep 8;26(3):319-330
pubmed: 25155756
Expert Rev Mol Diagn. 2020 Feb;20(2):141-150
pubmed: 31498685
Clin Cancer Res. 2014 Feb 15;20(4):890-903
pubmed: 24323898
Cancers (Basel). 2019 Sep 20;11(10):
pubmed: 31547070
J Clin Oncol. 2016 Sep 1;34(25):3005-13
pubmed: 27400947
Oncologist. 2019 May;24(5):612-616
pubmed: 30944184
Ann Transl Med. 2019 Nov;7(22):690
pubmed: 31930091
Anal Chem. 2017 Jan 17;89(2):1155-1162
pubmed: 27958721
Prostate Cancer Prostatic Dis. 2018 Jun;21(2):260-268
pubmed: 29302046
N Engl J Med. 2011 May 26;364(21):1995-2005
pubmed: 21612468
Eur Urol. 2012 Apr;61(4):810-7
pubmed: 22277196
BJU Int. 2017 Jun;119(6):854-861
pubmed: 28182321
Cancer Invest. 2002;20(3):324-32
pubmed: 12025227
Eur Urol. 2018 Jan;73(1):71-78
pubmed: 28592388
Cancer Cell. 2011 May 17;19(5):575-86
pubmed: 21575859
Nature. 2014 Mar 20;507(7492):315-22
pubmed: 24476821
N Engl J Med. 2018 Nov 01;379(18):1754-1765
pubmed: 30380390
Eur Urol. 2016 Jun;69(6):1062-4
pubmed: 26782348
J Hematol Oncol. 2018 Sep 10;11(1):114
pubmed: 30201021
J Pathol. 2007 Sep;213(1):91-8
pubmed: 17668422
Clin Cancer Res. 2001 Dec;7(12):4080-5
pubmed: 11751505
Ann Surg Oncol. 2020 Apr;27(4):1272-1281
pubmed: 31832914
Ann Oncol. 2009 Feb;20(2):305-8
pubmed: 18836088
Cancer Res. 1996 Oct 15;56(20):4556-61
pubmed: 8840959
Cancer. 2007 Apr 1;109(7):1439-45
pubmed: 17326057
Oncol Lett. 2016 Dec;12(6):4891-4895
pubmed: 28105198
Oncotarget. 2016 Mar 1;7(9):10547-56
pubmed: 26859683
Nature. 2013 Jul 4;499(7456):43-9
pubmed: 23792563
Science. 2012 Oct 12;338(6104):221
pubmed: 22923433
Eur Urol. 2014 Dec;66(6):1190-3
pubmed: 25587595
Cancer Med. 2014 Aug;3(4):835-44
pubmed: 24846059
Oncotarget. 2016 Sep 13;7(37):59877-59891
pubmed: 27494883
Cancer Cell. 2009 Jan 6;15(1):21-34
pubmed: 19111878
Eur Urol. 2017 Oct;72(4):544-554
pubmed: 28390739
Oncoimmunology. 2020 Mar 23;9(1):1738798
pubmed: 32391189
JAMA Oncol. 2016 Nov 01;2(11):1441-1449
pubmed: 27262168
Cancer Cell. 2011 Jun 14;19(6):792-804
pubmed: 21620777
Int J Mol Sci. 2020 Feb 21;21(4):
pubmed: 32098246
Cell. 2018 Jan 11;172(1-2):373-386.e10
pubmed: 29224780
Diagnostics (Basel). 2019 Aug 14;9(3):
pubmed: 31416266
Eur Urol. 2016 Jun;69(6):992-5
pubmed: 26724258
N Engl J Med. 2014 Sep 11;371(11):1028-38
pubmed: 25184630
Eur Urol. 2020 Jun;77(6):701-710
pubmed: 32165065
J Clin Oncol. 2017 Sep 10;35(26):2993-3001
pubmed: 28644771
Cancer Discov. 2014 Oct;4(10):1140-53
pubmed: 25096233
Gynecol Oncol. 2017 May;145(2):361-365
pubmed: 28274569
Eur Urol. 2015 Dec;68(6):959-67
pubmed: 26238431
Int J Cancer. 2014 Oct 15;135(8):1978-82
pubmed: 24599551
Nat Genet. 2016 Dec;48(12):1490-1499
pubmed: 27749842
Eur Urol. 2019 Jan;75(1):18-22
pubmed: 30266310
Int J Mol Sci. 2020 Apr 10;21(7):
pubmed: 32290245
PLoS One. 2020 Jan 27;15(1):e0226219
pubmed: 31986176
Clin Cancer Res. 2014 Apr 1;20(7):1955-64
pubmed: 24622468
J Nucl Med. 2016 Dec;57(12):1941-1944
pubmed: 27390158
Nat Protoc. 2014 Mar;9(3):694-710
pubmed: 24577360
Nat Rev Clin Oncol. 2017 Sep;14(9):531-548
pubmed: 28252003
BMC Cancer. 2011 Aug 04;11:336
pubmed: 21816094
JAMA Oncol. 2018 Sep 1;4(9):1179-1186
pubmed: 29955787
Anal Chem. 2014 Jun 17;86(12):6088-94
pubmed: 24892731
Front Oncol. 2018 Dec 21;8:653
pubmed: 30622933
N Engl J Med. 2012 Sep 27;367(13):1187-97
pubmed: 22894553
Int J Cancer. 2016 Jun 15;138(12):2894-904
pubmed: 26789903
Nat Med. 2018 Jun;24(6):749-757
pubmed: 29867230
PLoS One. 2016 Jul 26;11(7):e0159397
pubmed: 27459545
Transl Oncol. 2013 Aug 01;6(4):420-8
pubmed: 23908685
Semin Diagn Pathol. 2015 Mar;32(2):103-13
pubmed: 25758327
Cancers (Basel). 2019 Feb 07;11(2):
pubmed: 30736478
N Engl J Med. 2015 Oct 29;373(18):1697-708
pubmed: 26510020
Clin Cancer Res. 2016 May 15;22(10):2445-2452
pubmed: 26831717
PLoS One. 2012;7(4):e35976
pubmed: 22558290
Ther Adv Urol. 2017 Nov 22;10(2):65-77
pubmed: 29434674
BMC Cancer. 2016 Sep 22;16(1):744
pubmed: 27658492
Oncotarget. 2017 Jun 16;8(35):59527-59538
pubmed: 28938656
Eur Urol. 2017 Mar;71(3):417-425
pubmed: 27590317
N Engl J Med. 2016 Aug 4;375(5):443-53
pubmed: 27433846
Clin Cancer Res. 2018 Nov 15;24(22):5585-5593
pubmed: 30068710
Bladder Cancer. 2016 Oct 27;2(4):395-403
pubmed: 28035320
Histopathology. 2019 Jan;74(1):31-59
pubmed: 30565301
Lancet Oncol. 2015 Mar;16(3):338-48
pubmed: 25701170