A case of ROS1-rearranged lung adenocarcinoma with osteoblastic bone metastasis.
Osteoblastic bone metastases
ROS1-Rearranged lung adenocarcinoma
Journal
Respiratory medicine case reports
ISSN: 2213-0071
Titre abrégé: Respir Med Case Rep
Pays: England
ID NLM: 101604463
Informations de publication
Date de publication:
2020
2020
Historique:
received:
31
01
2020
revised:
06
06
2020
accepted:
09
06
2020
entrez:
25
6
2020
pubmed:
25
6
2020
medline:
25
6
2020
Statut:
epublish
Résumé
A 53-year-old woman was referred to our hospital for detailed examination of abnormal chest shadows recognized on CT imaging. Transbronchial lung biopsy of a right S6 nodular shadow led to a diagnosis of lung adenocarcinoma. FDG-PET-CT showed FDG accumulation in the Th11 and L2 vertebral bodies and osteoblastic bone lesions. Since osteoblastic bone metastasis in lung cancer is extremely rare, CT-guided bone biopsy was performed. The tumor was diagnosed as ROS1-rearranged lung adenocarcinoma, for which crizotinib was administered, which led to improvement of both the primary and metastatic lesions. We report here a rare case of ROS1-rearranged lung adenocarcinoma with osteoblastic bone metastasis of lung cancer.
Identifiants
pubmed: 32577365
doi: 10.1016/j.rmcr.2020.101124
pii: S2213-0071(20)30024-1
pii: 101124
pmc: PMC7303991
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101124Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
The authors state that they have no conflict of interest in regard to this manuscript.
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