The role of cigarette smoking on new-onset of chronic kidney disease in a Japanese population without prior chronic kidney disease: Iki epidemiological study of atherosclerosis and chronic kidney disease (ISSA-CKD).
Adult
Age Factors
Aged
Atherosclerosis
/ epidemiology
Cigarette Smoking
/ epidemiology
Female
Follow-Up Studies
Glomerular Filtration Rate
Humans
Incidence
Japan
/ epidemiology
Male
Middle Aged
Proportional Hazards Models
Proteinuria
/ epidemiology
Renal Insufficiency, Chronic
/ epidemiology
Retrospective Studies
Risk Factors
Chronic kidney disease
Estimated glomerular filtration rate
Japanese epidemiological study
Proteinuria
Smoking
Journal
Clinical and experimental nephrology
ISSN: 1437-7799
Titre abrégé: Clin Exp Nephrol
Pays: Japan
ID NLM: 9709923
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
02
04
2020
accepted:
10
06
2020
pubmed:
25
6
2020
medline:
5
8
2021
entrez:
25
6
2020
Statut:
ppublish
Résumé
Studies regarding harmful effects of smoking on the new-onset of chronic kidney disease (CKD) have been limited. Thus, we collected and retrospectively studied 8 years of data from the annual health check-ups of the residents in Iki City (Nagasaki Prefecture, Japan). From 2008 to 2016, 4540 adults were enrolled in the study. Information on smoking habits was obtained via a self-reported questionnaire. New-onset CKD was defined as a reduction of the estimated globular filtration rate (eGFR) to less than 60 mL/min/1.73 m During an average follow-up of 4.6 years, proteinuria developed in 218 people (10.4 per 1000 person-years) and eGFR decline to less than 60 mL/min/1.73 m Smoking significantly increased the risk for new-onset of CKD based on proteinuria development in a Japanese population without CKD, and the association was more predominant in the younger population.
Sections du résumé
BACKGROUND
BACKGROUND
Studies regarding harmful effects of smoking on the new-onset of chronic kidney disease (CKD) have been limited. Thus, we collected and retrospectively studied 8 years of data from the annual health check-ups of the residents in Iki City (Nagasaki Prefecture, Japan).
METHODS
METHODS
From 2008 to 2016, 4540 adults were enrolled in the study. Information on smoking habits was obtained via a self-reported questionnaire. New-onset CKD was defined as a reduction of the estimated globular filtration rate (eGFR) to less than 60 mL/min/1.73 m
RESULTS
RESULTS
During an average follow-up of 4.6 years, proteinuria developed in 218 people (10.4 per 1000 person-years) and eGFR decline to less than 60 mL/min/1.73 m
CONCLUSIONS
CONCLUSIONS
Smoking significantly increased the risk for new-onset of CKD based on proteinuria development in a Japanese population without CKD, and the association was more predominant in the younger population.
Identifiants
pubmed: 32577942
doi: 10.1007/s10157-020-01914-8
pii: 10.1007/s10157-020-01914-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM