Sleep-Disordered Breathing and 24-Hour Ambulatory Blood Pressure Monitoring in Renal Transplant Patients: Longitudinal Study.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
07 07 2020
Historique:
pubmed: 25 6 2020
medline: 10 3 2021
entrez: 25 6 2020
Statut: ppublish

Résumé

Background Sleep-disordered breathing (SDB) is considered a strong risk factor for hypertension in the general population. This disturbance is common in end-stage kidney disease patients on long-term hemodialysis and improves early on after renal transplantation. Whether SDB may be a risk factor for hypertension in renal transplant patients is unclear. Methods and Results We investigated the long-term evolution of simultaneous polysomnographic and 24-hour ambulatory blood pressure (BP) monitoring recordings in a cohort of 221 renal transplant patients. Overall, 404 paired recordings were made over a median follow-up of 35 months. A longitudinal data analysis was performed by the mixed linear model. The apnea-hypopnea index increased from a median baseline value of 1.8 (interquartile range, 0.6-5.0) to a median final value of 3.6 (interquartile range, 1.7-10.4;

Identifiants

pubmed: 32578469
doi: 10.1161/JAHA.120.016237
pmc: PMC7670525
doi:

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e016237

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Auteurs

Francesca Mallamaci (F)

Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Cal. National Research Council of Italy Center of Clinical Physiology c/o Ospedali Riuniti Reggio Calabria Italy.
Division of Nephrology and Transplantation Department of Medicine Ospedali Riuniti Reggio Calabria Italy.

Rocco Tripepi (R)

Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Cal. National Research Council of Italy Center of Clinical Physiology c/o Ospedali Riuniti Reggio Calabria Italy.

Graziella D'Arrigo (G)

Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Cal. National Research Council of Italy Center of Clinical Physiology c/o Ospedali Riuniti Reggio Calabria Italy.

Vincenzo Panuccio (V)

Division of Nephrology and Transplantation Department of Medicine Ospedali Riuniti Reggio Calabria Italy.

Giovanna Parlongo (G)

Division of Nephrology and Transplantation Department of Medicine Ospedali Riuniti Reggio Calabria Italy.

Graziella Caridi (G)

Division of Nephrology and Transplantation Department of Medicine Ospedali Riuniti Reggio Calabria Italy.

Maria Carmela Versace (MC)

Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Cal. National Research Council of Italy Center of Clinical Physiology c/o Ospedali Riuniti Reggio Calabria Italy.

Gianfranco Parati (G)

Department of Cardiovascular, Neural and Metabolic Sciences Istituto Auxologico Italiano IRCCS San Luca Hospital Milan Italy.
Department of Medicine and Surgery University of Milano-Bicocca Milan Italy.

Giovanni Tripepi (G)

Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Cal. National Research Council of Italy Center of Clinical Physiology c/o Ospedali Riuniti Reggio Calabria Italy.

Carmine Zoccali (C)

Clinical Epidemiology of Renal Diseases and Hypertension Unit, Reggio Cal. National Research Council of Italy Center of Clinical Physiology c/o Ospedali Riuniti Reggio Calabria Italy.

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