Temporal Trends in Angina, Myocardial Perfusion, and Left Ventricular Remodeling in Women With No Obstructive Coronary Artery Disease Over 1-Year Follow-Up: Results From WISE-CVD.
Adult
Aged
Angina Pectoris
/ diagnostic imaging
Cardiovascular Agents
/ therapeutic use
Coronary Circulation
/ drug effects
Female
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Middle Aged
Myocardial Ischemia
/ diagnostic imaging
Myocardial Perfusion Imaging
Prospective Studies
Recovery of Function
Risk Assessment
Risk Factors
Sex Factors
Surveys and Questionnaires
Time Factors
Treatment Outcome
United States
Ventricular Function, Left
/ drug effects
Ventricular Remodeling
/ drug effects
angina
cardiovascular magnetic resonance imaging
ischemic heart disease
left ventricular remodeling
quality of life
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
07 07 2020
07 07 2020
Historique:
pubmed:
25
6
2020
medline:
10
3
2021
entrez:
25
6
2020
Statut:
ppublish
Résumé
Background Women with ischemia and no obstructive coronary artery disease are increasingly recognized and found to be at risk for major adverse cardiovascular events. Methods and Results In 214 women with suspected ischemia and no obstructive coronary artery disease who completed baseline and 1-year follow-up vasodilatory stress cardiac magnetic resonance imaging, we investigated temporal trends in angina (Seattle Angina Questionnaire [SAQ]), myocardial perfusion reserve index, blood pressure, and left ventricular (LV) remodeling and function from baseline to 1-year follow-up and explored associations between these different parameters. We observed concordant positive trends in 4/5 SAQ domains, SAQ-7, myocardial perfusion reserve index, blood pressure, LV mass, and LV mass-to-volume ratio. There was no association between SAQ-7 improvement and myocardial perfusion reserve index improvement over 1-year follow-up (
Identifiants
pubmed: 32578481
doi: 10.1161/JAHA.119.016305
pmc: PMC7670509
doi:
Substances chimiques
Cardiovascular Agents
0
Banques de données
ClinicalTrials.gov
['NCT02582021']
Types de publication
Journal Article
Multicenter Study
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e016305Subventions
Organisme : NIA NIH HHS
ID : R03 AG032631
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000124
Pays : United States
Organisme : NHLBI NIH HHS
ID : UM1 HL087366
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HV68162
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01 HV068164
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL090957
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL151867
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001427
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL125941
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01 HV068161
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL069751
Pays : United States
Organisme : NCRR NIH HHS
ID : M01 RR000425
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000064
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HV68163
Pays : United States
Organisme : NHLBI NIH HHS
ID : K23 HL105787
Pays : United States
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