Cytoarchitectural analysis of the neuron-to-glia association in the dorsal root ganglia of normal and diabetic mice.


Journal

Journal of anatomy
ISSN: 1469-7580
Titre abrégé: J Anat
Pays: England
ID NLM: 0137162

Informations de publication

Date de publication:
11 2020
Historique:
received: 23 04 2020
revised: 22 05 2020
accepted: 22 05 2020
pubmed: 25 6 2020
medline: 26 5 2021
entrez: 25 6 2020
Statut: ppublish

Résumé

Dorsal root ganglia (DRGs) host the somata of sensory neurons which convey information from the periphery to the central nervous system. These neurons have heterogeneous size and neurochemistry, and those of small-to-medium size, which play an important role in nociception, form two distinct subpopulations based on the presence (peptidergic) or absence (non-peptidergic) of transmitter neuropeptides. Few investigations have so far addressed the spatial relationship between neurochemically different subpopulations of DRG neurons and glia. We used a whole-mount mouse lumbar DRG preparation, confocal microscopy and computer-aided 3D analysis to unveil that IB4

Identifiants

pubmed: 32579747
doi: 10.1111/joa.13252
pmc: PMC7542191
doi:

Substances chimiques

Glycoproteins 0
isolectin B4-binding glycoprotein, mouse 0
Glutamate-Ammonia Ligase EC 6.3.1.2
Calcitonin Gene-Related Peptide JHB2QIZ69Z

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

988-997

Informations de copyright

© 2020 Anatomical Society.

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Auteurs

Elisa Ciglieri (E)

Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
Max Planck Institute for Metabolism Research, Cologne, Germany.

Maurizia Vacca (M)

Department of Control and Computer Engineering, Politecnico di Torino, Torino, Italy.

Francesco Ferrini (F)

Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
Department of Psychiatry & Neuroscience, Université Laval, Québec, QC, Canada.

Mona A Atteya (MA)

Department of Biochemistry, Faculty of Science, Alexandria University, Alexandria, Egypt.

Patrizia Aimar (P)

Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.

Elisa Ficarra (E)

Department of Control and Computer Engineering, Politecnico di Torino, Torino, Italy.

Santa Di Cataldo (S)

Department of Control and Computer Engineering, Politecnico di Torino, Torino, Italy.

Adalberto Merighi (A)

Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.
National Institute of Neuroscience, Grugliasco, Italy.

Chiara Salio (C)

Department of Veterinary Sciences, University of Turin, Grugliasco, Italy.

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Classifications MeSH