Biopsychosocial factors associated with a current depressive episode in diabetes: the ELSA-Brasil study.
Adult
Age Factors
Alcohol Drinking
/ epidemiology
Black People
Brazil
/ epidemiology
Cardiovascular Diseases
/ epidemiology
Case-Control Studies
Cholesterol, HDL
/ blood
Creatinine
/ blood
Depressive Disorder
/ psychology
Diabetes Mellitus
/ psychology
Educational Status
Female
Financial Stress
Humans
Income
Insulin Resistance
Logistic Models
Male
Middle Aged
Models, Biopsychosocial
Multivariate Analysis
Serum Albumin
Sex Factors
Social Discrimination
Waist Circumference
Journal
Diabetic medicine : a journal of the British Diabetic Association
ISSN: 1464-5491
Titre abrégé: Diabet Med
Pays: England
ID NLM: 8500858
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
accepted:
18
06
2020
pubmed:
25
6
2020
medline:
3
11
2021
entrez:
25
6
2020
Statut:
ppublish
Résumé
Depression is more prevalent in people with diabetes, and is associated with worse diabetes outcomes. Depression in diabetes is more treatment resistant, and as underlying mechanisms are unknown, development of more effective treatment strategies is complicated. A biopsychosocial model may improve our understanding of the pathophysiology, and therewith help improving treatment options. Diabetes was diagnosed according to American Diabetes Association (ADA) criteria and a current depressive episode according to the International Classification of Diseases (ICD-10), based on the Clinical Interview Schedule Revised (CIS-R). From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), we included 455 participants without diabetes with a current depressive episode and 10 900 without either diabetes or a current depressive episode. Furthermore, 2183 participants had diabetes alone and 106 had both diabetes and a current depressive episode. Variable selection was based on their relationship with depression and/or diabetes. Multinomial multivariate logistic regression was used to determine how the models differed between participants with and without diabetes. A current depressive episode in diabetes was related to being older and female, having poorer education, financial problems, experiencing discrimination at work, home and school, higher waist circumference, albumin to creatinine ratio and insulin resistance, and the presence of hypertension and cardiovascular disease. In non-diabetes, a current depressive disorder was related to being female, not being black, low income, psychological and social factors, non-current alcohol use, lower HDL cholesterol, higher insulin resistance and the presence of cardiovascular disease. A current depressive episode in the presence compared with the absence of diabetes was related more to biological than to psychosocial factors.
Identifiants
pubmed: 32580244
doi: 10.1111/dme.14349
pmc: PMC7540479
doi:
Substances chimiques
Cholesterol, HDL
0
Serum Albumin
0
Creatinine
AYI8EX34EU
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1742-1751Subventions
Organisme : Ministério da Saúde
Pays : International
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
Pays : International
Organisme : Financiadora de Estudos e Projetos
Pays : International
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Pays : International
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.
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